Results 81 to 90 of about 41,997 (234)

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

Resúmenes de investigaciones nacionales. Nutrición normal y terapéutica

Perspectivas en Nutrición Humana, 2008
Objetivo: evaluar el efecto del suplemento de retinol sobre citocinas en niños con malaria vivax no complicada. Metodología: estudio piloto, experimental, balanceado no ciego, con asignación aleatoria del "factor de exposición" (recibir o no, suplemento ...
Viviana Milena Taylor Orozco, Rosa Magdalena Uscátegui Peñuela, Jaime Carmona Fonseca, Adriana Correa Botero   +3 more
doaj  

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Serum retinol concentration and prevalence of vitamin A deficiency in postpartum women [PDF]

Revista Brasileira em Promoção da Saúde, 2011
Objective: To check the serum retinol concentration and assess the nutritional status of postpartum women assisted at Januario Cicco Maternity School, Natal / RN in relation to vitamin A deficiency.
Juliana Cristina de Oliveira Dantas, Ana Caroline Perez Medeiros, Karla Danielly da Silva Ribeiro Rodrigues, Roberto Dimenstein   +3 more
doaj  

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

Associations between serum retinol and all-cause mortality among adults with prediabetes and diabetes: A cohort study.

PLoS ONE
We aimed to explore the associations between serum retinol and all-cause mortality among people with prediabetes and diabetes. The study included 2582 participants with prediabetes and 1654 with diabetes aged ≥40 years from the National Health and ...
Qing Sun, Jie Guo
doaj   +1 more source

Evaluating the suitability of six hydrophobic natural eutectic solvents as the internal phase in a cosmetic cream formulation

International Journal of Cosmetic Science, EarlyView.
Hydrophobic natural eutectic solvents can function as structural oil phase substitutes in creams prepared by low‐energy processes, enabling sustainable, regulation‐compliant formulations with desirable sensory profiles. Abstract Objective This work evaluates whether hydrophobic natural eutectic solvents can replace the conventional oil phase in ...
A. Verger, R. Grard, E. Vrignaud, X. Perse, S. Bouderbala, L. Boudesocque‐Delaye, M. Grisel, E. Gore, E. Munnier   +8 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms

Scientific Reports
Retinol and retinoids can effectively intervene skin aging process, but usually induce skin intolerance. In this study, we aimed to determine the synergistic anti-aging effects of retinol and two retinol derivatives-hydroxypinacolone retinoate (HPR) and ...
Jingyin Zhang, Zhuojun Li, Xiaoping Song, Panpan Cai, Qingchao Liu   +4 more
doaj   +1 more source

Physicochemical Quality and Chemical Safety of Commercial Wet Cat Food: Composition, Oxidation, Biogenic Amines, and Trace Elements

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study investigated the physicochemical characteristics and chemical safety of commercial wet cat foods marketed in Brazil. Twenty products labeled as beef, chicken and fish flavors were analyzed for proximate composition, pH, lipid and protein oxidation, biogenic amines, and essential and potentially toxic trace elements.
Marina Teixeira de Vries Mársico, Eliane Teixeira Mársico, Celso Fasura Balthazar, João Paulo de Sá Felizardo, Roberto Meigikos dos Anjos, Erick Almeida Esmerino, Sérgio Borges Mano   +6 more
wiley   +1 more source