Results 41 to 50 of about 40,792 (218)

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Retinol Depletion in COVID-19

Clinical Nutrition Open Science, 2022
Summary: Background and aims: COVID-19 has been a devastating pandemic. There are indications that vitamin A is depleted during infections. Vitamin A is important in development and immune homeostasis.
Aziz Rodan Sarohan, Hakan Akelma, Eşref Araç, Özgür Aslan, Osman Cen   +4 more
doaj   +1 more source

Understanding protein–flavor interactions: Factors, characterization techniques, and the effect of processing

Food Biomacromolecules, EarlyView.
Abstract The perception of flavor in a food system depends on its release from the protein matrix. Apart from hydrogen bonding, hydrophobic interactions and van der Waal's forces, the formation of covalent adducts between the flavor and protein highly impacts the release of flavor from the protein matrix.
Arshita Verma, Somnath Basak, Rekha S. Singhal   +2 more
wiley   +1 more source

Genetic influences on circulating retinol and its relationship to human health

Nature Communications
Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest genome-wide association study (GWAS) of retinol to date in up to 22,274 participants. We identify eight
William R. Reay, Dylan J. Kiltschewskij, Maria A. Di Biase, Zachary F. Gerring, Kousik Kundu, Praveen Surendran, Laura A. Greco, Erin D. Clarke, Clare E. Collins, Alison M. Mondul, Demetrius Albanes, Murray J. Cairns   +11 more
doaj   +1 more source

Plasma kinetics of vitamin A in humans after a single oral dose of [8,9,19-13C]retinyl palmitate

Journal of Lipid Research, 1996
The kinetics of vitamin A and its major metabolites were investigated in humans. Eleven healthy male subjects ingested 105 mumol (100,000 IU) of [8,9,19-13C]retinyl palmitate in an oily solution.
D V Reinersdorff, E Bush, D J Liberato
doaj   +1 more source

Níveis plasmáticos de vitamina A em crianças carentes com pneumonia na fase aguda e após recuperação Plasma vitamin A levels in deprived children with pneumonia during the acute phase and after recovery

Jornal de Pediatria, 2005
OBJETIVO: Comparar os níveis plasmáticos de retinol em crianças de baixo nível socioeconômico com pneumonia, antes e depois da resolução do processo infeccioso; investigar a associação entre os níveis plasmáticos de retinol, após a resolução da infecção,
Rosangela da Silva, Emílio Lopes Jr., Roseli Oselka Saccardo Sarni, José Augusto de Aguiar Carrazedo Taddei   +3 more
doaj   +1 more source

Utilidad de un método que determina simultáneamente retinol y α-tocoferol en leche materna por cromatografía líquida de alta resolución

Perinatología y Reproducción Humana, 2016
Objetivo: Reportar la utilidad de un método simplificado con extracción directa de la leche materna y detección por cromatografía líquida de alta resolución en fase inversa, para la cuantificación de retinol y α-tocoferol.
H. Martínez-Rojano, R. Sámano, M. Tolentino, R.M. Morales Hernández, C. Ramírez, M.L. Pizano Zárate   +5 more
doaj   +1 more source

Associations between Nugent‐bacterial vaginosis and preterm birth and other adverse pregnancy outcomes in rural northwestern Bangladesh

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Bacterial vaginosis, defined by Nugent score (Nugent‐BV), has been associated with preterm birth and other adverse pregnancy outcomes. However, few studies have longitudinally described the associations between Nugent‐BV and adverse pregnancy outcomes at varying times in pregnancy.
Daniel J. Erchick, Susan Tuddenham, Lena Kan, Lee S. F. Wu, Alain B. Labrique, Hasmot Ali, Ethan K. Gough, Mahbubur Rashid, Towfida J. Siddiqua, Subhra Chakraborty, Pawel Gajer, Michael France, Jacques Ravel, Golsa M. Yazdy, Keith P. West, Parul Christian   +15 more
wiley   +1 more source

Cellular retinol-binding protein (type two) is abundant in human small intestine.

Journal of Lipid Research, 1987
Human small intestine was found to contain a retinol-binding protein similar to the gut-specific cellular retinol-binding protein, type two [CRBP (II)], described in the rat.
D E Ong, D L Page
doaj   +1 more source