Results 51 to 60 of about 37,733 (224)

Regulation of retinol uptake and esterification in MCF-7 and HepG2 cells by exogenous fatty acids

Journal of Lipid Research, 1991
The influence of extracellular fatty acids on the uptake and esterification of [3H]retinol bound to human retinol-binding protein (RBP), to RBP-transthyretin (TTR), or in dispersed form by the human hepatoma, HepG2, and human mammary epithelial carcinoma,
RK Randolph, AC Ross
doaj  

Selective biosynthesis of retinol in S. cerevisiae

Bioresources and Bioprocessing, 2022
AbstractThe vitamin A component retinol has become an increasingly sought-after cosmetic ingredient. In previous efforts for microbial biosynthesis of vitamin A, a mixture of retinoids was produced. In order to efficiently produce retinol at high purity, the precursor and NADPH supply was first enhanced to improve retinoids accumulation in the S ...
Qiongyue Hu, Tanglei Zhang, Hongwei Yu, Lidan Ye   +3 more
openaire   +3 more sources

Hydrogel Composites and Their Potential Application in Animal Production and Health

Animal Research and One Health, EarlyView.
With emerging concerns about environmental contamination and safe animal production practices for increased animal welfare, research has increased in search of alternatives to promote sustainable production. The application of naturally derived hydrogels presents a great opportunity for exploration and application for animal production purposes ...
Victoria Anthony Uyanga, Tolulope Grace Ogundipe, Onome Ejeromedoghene, Abigail Adamma Ere‐Richard, Edikan Effiong Okon   +4 more
wiley   +1 more source

Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial. [PDF]

J Cosmet Dermatol
ABSTRACT Background The functionality and regenerative capacity of skin progressively deteriorate with aging. Topical use of peptides with a hyper‐safety profile has been implicated in replacing retinol for skin anti‐aging use, but is limited due to low stability and poor skin permeability.
Chang H, Tao K, Yang Y, Wang Y, Ge M, Wang X, Tang S, Yu H.   +7 more
europepmc   +2 more sources

Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Plasma transferrin (Tf) is the transport protein central to the process of iron recycling and metabolism. Holo‐Tf serves as the body's pool of ferric iron, facilitating transport from tissues such as the intestine, liver, spleen, and finally bone marrow, where iron is incorporated into erythropoiesis.
Shuwei Lu, Mohd A. Khan, Saini Setua, Quintin O'Boyle, Kiruphagaran Thangaraju, Pedro Cabrales, Delaney C. Swindle, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +9 more
wiley   +1 more source

The Transfer of Retinol from Serum Retinol-binding Protein to Cellular Retinol-binding Protein Is Mediated by a Membrane Receptor [PDF]

Journal of Biological Chemistry, 1998
The hypothesis that the cellular uptake of retinol involves the specific interaction of a plasma membrane receptor with serum retinol-binding protein (RBP) at the extracellular surface followed by ligand transfer to cytoplasmic cellular retinol-binding protein (CRBP) has been investigated.
Asipu Sivaprasadarao, John B. C. Findlay, Manickavasagam Sundaram, Monica M. DeSousa   +3 more
openaire   +3 more sources

Brazilian Biomes as Promising Resources of Rhodotorula Yeasts for the Biotechnological Production of Carotenoids

Chemistry &Biodiversity, EarlyView.
ABSTRACT Yeasts belonging to the genus Rhodotorula are capable of synthesizing carotenoids, such as β‐carotene, γ‐carotene, torulene, torularodine, and astaxanthin. These carotenoids have been shown to offer health benefits to humans, such as immune system strengthening and a reduced risk of chronic degenerative diseases.
David Cristian Rodrigues Lucas, Renan Campos Chisté   +1 more
wiley   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

ChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang, Nataliia Lukianenko, Ja‐Hyun Baik, Yun Kyung Kim, Sungsu Lim   +4 more
wiley   +1 more source

A rapid versatile microassay for cellular retinol-binding protein using Lipidex-1000 microcolumns.

Journal of Lipid Research, 1990
A new, rapid and versatile microassay for cellular retinol-binding protein has been developed based on separation of bound and free ligand by means of Lipidex-1000, a hydrophobic Sephadex derivative.
A M Timmers, D A van Groningen-Luyben, F J Daemen, W J De Grip   +3 more
doaj  

Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case–control study in a Korean population

Scientific Reports, 2023
This study aimed to examine whether the ISX rs5755368 genotypes are associated with the effect of dietary retinol consumption on CRC risk. We recruited 923 CRC patients and 1846 controls to identify the association between dietary retinol and CRC risk ...
Anh Quynh Bui, Madhawa Gunathilake, Jeonghee Lee, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin, Jeongseon Kim   +7 more
doaj   +1 more source