Adipokine Retinol Binding Protein 4 and Cardiovascular Diseases [PDF]
Frontiers in Physiology, 2022 The morbidity and mortality of cardiovascular diseases (CVDs) have been increasing year by year all over the world and expanding greatly to the younger population, which becomes the leading causes of death globally that threatens human life safety ...
Yanjing Ji +3 more
doaj +6 more sources
Retinol-binding protein-4 and nonalcoholic fatty liver disease [PDF]
Chinese Medical Journal, 2022 . Nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common as the global economy grows and living standards improve. Timely and effective preventions and treatments for NAFLD are urgently needed.
Hangkai Huang, Chengfu Xu, Yuanyuan Ji
doaj +5 more sources
Retinol and Retinol Binding Protein 4 Levels and Cardiometabolic Disease Risk. [PDF]
Circ Res, 2022 Background: Despite mechanistic studies linking retinol and RBP4 (retinol binding protein 4) to the pathogenesis of cardiovascular diseases (CVD) and type 2 diabetes (T2D), epidemiological evidence is still conflicting.
Schiborn C +10 more
europepmc +9 more sources
Interplay between Fatty Acid Binding Protein 4, Fetuin-A, Retinol Binding Protein 4 and Thyroid Function in Metabolic Dysregulation [PDF]
Metabolites, 2022 Signalling between the tissues integrating synthesis, transformation and utilization of energy substrates and their regulatory hormonal axes play a substantial role in the development of metabolic disorders.
Daniela Dadej +2 more
doaj +3 more sources
The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review. [PDF]
Int J Environ Res Public Health, 2022 Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a ...
Ratajczyk K +8 more
europepmc +5 more sources
Retinol Binding Protein 4 Promotes Chondrocyte and Osteoclast Differentiation [PDF]
BiologyRetinol-binding protein 4 (RBP4), an adipokine secreted by adipose tissues, has been implicated in metabolic inflammation and insulin resistance. Type 2 diabetes (T2D) is a recognized risk factor for osteoarthritis, with both conditions characterized by ...
Adam Quincey +2 more
doaj +4 more sources
Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study [PDF]
BMC Pulmonary MedicineBackground The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang +5 more
doaj +4 more sources
A Label-Free Gold Nanoparticles-Based Optical Aptasensor for the Detection of Retinol Binding Protein 4 [PDF]
Biosensors, 2022 Retinol-binding protein 4 (RBP4) has been implicated in insulin resistance in rodents and humans with obesity and T2DM, making it a potential biomarker for the early diagnosis of T2DM.
Koena L. Moabelo +6 more
doaj +3 more sources
Elevated Serum Retinol Binding Protein 4 is Associated with the Risk of Diabetic Cardiomyopathy [PDF]
Reviews in Cardiovascular Medicine, 2022 Background: Retinol binding protein 4 (RBP4), a biomarker for insulin resistance in type 2 diabetes (DM), is increased in heart failure. This case-control study aims to determine the association between serum RBP4 levels and diabetic cardiomyopathy (DCM).
Haihua Shan +8 more
doaj +4 more sources
Retinol-binding protein 4 in obesity and metabolic dysfunctions.
Molecular and Cellular Endocrinology, 2021 Excessive increased adipose tissue mass in obesity is associated with numerous co-morbid disorders including increased risk of type 2 diabetes, fatty liver disease, hypertension, dyslipidemia, cardiovascular diseases, dementia, airway disease and some ...
P. A. Nono Nankam, M. Blüher
semanticscholar +4 more sources