Results 131 to 140 of about 185,541 (306)

Metabolism of Butoxyethanol in excised human skin in vitro [PDF]

, 2008
Glycol ethers are widely used in industrial and household applications because their chemical and physical properties make them versatile solvents, miscible with both water and organic media.
Traynor, M.J., Wilkinson, S.C., Williams, F.M.   +2 more
core   +1 more source

Retinol-binding protein 4 (RBP4) and high sensitivity C-reactive protein (hs-CRP) levels in patients with diminished ovarian reserve (DOR): a cross-sectional study

Reproductive Biology and Endocrinology, 2020
Background Antioxidant/oxidant imbalance has been reported to be related to diminished ovarian reserve (DOR). Vitamin A (retinol), a kind of antioxidant, plays a role in restoring ovarian oxidative damage, while C-reactive protein (CRP) is the classical ...
Wen Zou, Zehao Wang, Jing-sheng Xia, Jing Yang   +3 more
semanticscholar   +1 more source

Type 2 Diabetes Mellitus and Retinol-Binding Protein 4

Korean Diabetes Journal, 2008
New function of retinol-binding protein 4 (RBP4) was identified in addition to the traditional role as a vitamin A transport protein. In the state of insulin resistance even before the onset of type 2 DM, GLUT4 expression by adipocytes is decreased, but those by skeletal muscle is well preserved.
Won-Young Lee, Eun-Jung Rhee
openaire   +1 more source

Serum Retinol-Binding Protein 4 Levels in Patients with Diabetic Retinopathy [PDF]

Journal of International Medical Research, 2010
Retinol-binding protein 4 (RBP4) has been reported to be involved in the development of insulin resistance and diabetes. This study was designed to investigate serum levels of RBP4 in patients with type 2 diabetes with and without diabetic retinopathy.
Z-Z, Li, X-Z, Lu, J-B, Liu, L, Chen
openaire   +2 more sources

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Retinoic acid as a modulator of T cell immunity [PDF]

, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R., Fernandez, D., Flores-Santibañez, F, Rosemblatt, M., Sauma, D., Tejon, G.   +5 more
core   +1 more source

Vitamin A metabolism is changed in donors after living-kidney transplantation: an observational study

Lipids in Health and Disease, 2011
Background The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin.
Henze Andrea, Raila Jens, Kempf Caroline, Reinke Petra, Sefrin Anett, Querfeld Uwe, Schweigert Florian J   +6 more
doaj   +1 more source

Retinol Binding Protein 4 (RBP4) in Adipocytes and Obesity

The FASEB Journal, 2019
We have earlier reported the generation and study of transgenic mice that express human RBP4 (hRBP4) in both white and brown adipocytes (Lee et al. Hepatology 2016, 64:1534–1546). Our published studies of these mice (adi‐hRBP4 mice) established that
Igor Shmarakov, Seung‐Ah Lee, William S. Blaner   +2 more
openaire   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

Comparative pharmacokinetics and pharmacodynamics of the advanced Retinol-Binding Protein 4 antagonist in dog and cynomolgus monkey

PLoS ONE, 2020
Accumulation of lipofuscin bisretinoids in the retina contributes to pathogenesis of macular degeneration. Retinol-Binding Protein 4 (RBP4) antagonists reduce serum retinol concentrations thus partially reducing retinol delivery to the retina which ...
B. Rácz, A. Váradi, P. Pearson, K. Petrukhin   +3 more
semanticscholar   +1 more source