Results 141 to 150 of about 16,382,176 (245)

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorizin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, Volume 4, Issue 3, September 2026.
We constructed a Pt‐TiO2 mesoporous nanocarrier to co‐deliver phlorizin for HCC synergistic sonodynamic‐chemoimmunotherapy. This nanoplatform targets DDX5 to remodel tumor metabolism, triggers mitochondrial damage, suppresses tumor proliferation, and elicits potent anti‐tumor immune responses by activating T cells and boosting immune cytokines in mice.
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Retinol binding protein 4 in patients as a marker for acute myocardial infarction with obesity as a predisposing factor: a scoping review

Heliyon
Acute myocardial infarction (AMI), a critical manifestation of ischemic heart disease, significantly contributes to global cardiovascular mortality. This study explores the role of retinol binding protein 4 (RBP4), which is linked to both obesity and AMI.
Femmy Widya Silvy, Sunita Sunita, Raden Aliya T.M. Djajanagara, Mohammad Rizki Akbar, Mas Rizky A.A. Syamsunarno   +4 more
doaj   +1 more source

Identification of lncRNAs in Breast Cancer Through Bioinformatics Analysis: Implications for Pathogenesis and Prognostic Significance

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Objective Breast cancer (BC) is a disease with a subtle onset, often diagnosed late, and has a high mortality rate. This study aimed to identify long non‐coding RNAs (lncRNAs) linked to BC as prognostic markers using bioinformatics and initial experiments, explore their regulatory pathways, and assess their expression and prognostic ...
Yuhan Zheng, Xinggui Chen, Xuan Liu, Yijin Zhou, Pei Yang, Shuhui Li   +5 more
wiley   +1 more source

Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley   +1 more source

Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS‐Responsive Therapeutics

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Breast cancer is the most frequently diagnosed malignancy among women worldwide, with 2.3 million new cases and approximately 670,000 deaths reported in 2022 alone. Despite advances in therapy, metastasis and acquired drug resistance remain major clinical challenges.
Marija Nikolovska, Radoslav Stojchevski, Aleksandar Eftimov, Mitko Mladenov, Dimiter Avtanski, Nikola Hadzi‐Petrushev   +5 more
wiley   +1 more source

Characterization of structural features of food molten‐globule state proteins: An overview

Food Biomacromolecules, Volume 3, Issue 3, Page 706-717, September 2026.
Abstract During food processing, pH, ionic strength, and temperature drive conformational transitions from native states to partially folded intermediates and fully unfolded states. The molten‐globule (MG) state typically preserves substantial secondary structure but has relaxed tertiary packing, thereby modulating protein solubility, emulsifying ...
Han Peng, Changyu Zhou, Daodong Pan, Jinxuan Cao, Qiang Xia   +4 more
wiley   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, Volume 2, Issue 3, September 2026.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Association between retinol binding protein-4 and psoriasis vulgaris: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne), 2023
Gao G, Cui Y, Cheng H.
europepmc   +1 more source

Calpeptin Reduces Extracellular Vesicle Secretion and Induces Anti‐Inflammatory Effects but Upregulates HO‐1 and Alters Adiponectin Levels in Human Adipocytes

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Recent studies have shown that adipose tissue (AT) secretes elevated levels of extracellular vesicles (EVs) in obesity, and these EVs play roles in metabolic diseases. The inhibition of calpains has anti‐inflammatory and anti‐fibrotic effects on AT in mice and reduces EV secretion in some cell types in vitro.
Johanna Matilainen, Sanni Foster, Viivi Berg, Janne Tampio, Tanja Turunen, Anne‐Mari Mustonen, Heikki Kyykallio, Maija Vaittinen, Ville Männistö, Jussi Pihlajamäki, Marjo Malinen, Sanna Oikari, Pirjo Käkelä, Dorota Kaminska, Veera Luukkonen, Kristiina M. Huttunen, Martin Wabitsch, Petteri Nieminen, Kirsi Rilla   +18 more
wiley   +1 more source

Role of retinol binding protein 4 in hepatic steatosis [PDF]

Hepatology, 2014
openaire   +2 more sources