Results 161 to 170 of about 16,382,176 (245)

Urotensin II Receptor Deletion Mitigates Kidney Injury and Renal Lipid Remodeling in Mice Fed a Long‐Term High‐Fat Diet

open access: yesFASEB BioAdvances, Volume 8, Issue 9, September 2026.
Urotensin II receptor deletion mitigates high‐fat diet‐induced kidney injury and renal lipid remodeling. Male wild‐type (WT) and urotensin II receptor–knockout (UT KO) mice were fed a high‐fat diet (HFD; 60% kcal from fat) for 33 weeks. In cultured mouse podocytes, urotensin II (UII)–UT signaling enhanced transient receptor potential canonical 6 (TRPC6)
Praghalathan Kanthakumar   +1 more
wiley   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

open access: yesAndrology, Volume 14, Issue 6, Page 1472-1478, September 2026.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik   +3 more
wiley   +1 more source

Interplay of retinol binding protein 4 with obesity and associated chronic alterations (Review). [PDF]

open access: yesMol Med Rep, 2022
Flores-Cortez YA   +5 more
europepmc   +1 more source

Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo

open access: yesActa Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Free fatty acids (FFAs) are hydrophobic and therefore cannot enter the bloodstream at appreciable levels unless they are solubilized by FFA carriers. Albumin has been appreciated for years as the major FFA carrier, but it is not the only carrier.
Gregory C. Henderson   +2 more
wiley   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Physicochemical Quality and Chemical Safety of Commercial Wet Cat Food: Composition, Oxidation, Biogenic Amines, and Trace Elements

open access: yesJournal of Animal Physiology and Animal Nutrition, Volume 110, Issue 5, Page 663-673, September 2026.
ABSTRACT This study investigated the physicochemical characteristics and chemical safety of commercial wet cat foods marketed in Brazil. Twenty products labeled as beef, chicken and fish flavors were analyzed for proximate composition, pH, lipid and protein oxidation, biogenic amines, and essential and potentially toxic trace elements.
Marina Teixeira de Vries Mársico   +6 more
wiley   +1 more source

Structure of chicken plasma retinol-binding protein

open access: yes, 2001
The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a = 46.06(5) Angstrom, b = 53.56(6) Angstrom, c = 73.41(8) Angstrom, and one protein
BEDA M   +5 more
core  

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