Results 11 to 20 of about 50,629 (277)

Electrochemical Aptasensing Platform for the Detection of Retinol Binding Protein-4 [PDF]

Biosensors
Here, we present the results of our the electrochemical aptasensing strategy for retinol binding protein-4 (RBP-4) detection based on a thiolated aptamer against RBP-4 and 6-mercaptohexanol (MCH) directly immobilized on a gold electrode surface. The most
Kamila Malecka-Baturo, Paulina Żółtowska, Agnieszka Jackowska, Katarzyna Kurzątkowska-Adaszyńska, Iwona Grabowska   +4 more
doaj   +2 more sources

Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection [PDF]

PLoS Pathogens
Viruses hijack host cell machinery to facilitate their own replication. Therefore, identifying key cellular factors and processes involved in viral infection is crucial for developing host-directed therapies.
Hejiao Zhao, Yalu Zhang, Qingbing Han, Huanan Li, Wenjun Liu, Lei Sun, Yingli Shang   +6 more
doaj   +3 more sources

Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein [PDF]

Communications Biology
Autophagy is a highly conserved degradative process that has been linked to various functions, including defending host cells against pathogens. Although the involvement of autophagy in porcine circovirus 2 (PCV2) infection has become apparent, it ...
Qingbing Han, Hejiao Zhao, Meng Chen, Wenshuo Xue, Jun Li, Lei Sun, Yingli Shang   +6 more
doaj   +2 more sources

A Label-Free Gold Nanoparticles-Based Optical Aptasensor for the Detection of Retinol Binding Protein 4 [PDF]

Biosensors, 2022
Retinol-binding protein 4 (RBP4) has been implicated in insulin resistance in rodents and humans with obesity and T2DM, making it a potential biomarker for the early diagnosis of T2DM.
Koena L. Moabelo, Teresa M. Lerga, Miriam Jauset-Rubio, Nicole R. S. Sibuyi, Ciara K. O’Sullivan, Mervin Meyer, Abram M. Madiehe   +6 more
doaj   +2 more sources

Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression [PDF]

Journal of Lipid Research, 2022
Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. However,
Julia S. Steinhoff, Carina Wagner, Ulrike Taschler, Sascha Wulff, Marie F. Kiefer, Konstantin M. Petricek, Sylvia J. Wowro, Moritz Oster, Roberto E. Flores, Na Yang, Chen Li, Yueming Meng, Manuela Sommerfeld, Stefan Weger, Andrea Henze, Jens Raila, Achim Lass, Michael Schupp   +17 more
doaj   +2 more sources

Retinol-binding protein 4 versus albuminuria as predictors of estimated glomerular filtration rate decline in patients with type 2 diabetes

Journal of Research in Medical Sciences, 2018
Background: Since the increase in some tubular damage biomarkers can be observed at the early stage of diabetic nephropathy, even in the absence of albuminuria, we aimed to investigate if urinary albumin is superior than tubular damage marker, such as ...
Aleksandra Klisic, Nebojsa Kavaric, Ana Ninic   +2 more
doaj   +3 more sources

Retinol Binding Protein 4 in Non Obese Psoriatic Cases [PDF]

Journal of Clinical and Diagnostic Research, 2016
Ola Ahmed Bakry, Mohamed Abdel Moneim Shoeib, Iman Masoud Abdel Gayed, Amany Said El Menoufy   +3 more
doaj   +3 more sources

Retinol-binding protein 4 in neonates born small for gestational age [PDF]

Journal of Endocrinological Investigation, 2010
Retinol-binding protein 4 (RBP4) is an adipocyte-derived 'signal' that may contribute to the pathogenesis of insulin resistance and Type 2 diabetes. The relationship of RBP4 with insulin resistance and metabolic risk in human beings has been the subject of several studies.
Bartoli, A, Boldrini, A, Cianfarani, S, Germani, D, Ghirri, P, Giacomozzi, C, Lapolla, R, Scirè, G, Serino, L   +8 more
core   +6 more sources

Role of retinol binding protein 4 in hepatic steatosis [PDF]

Hepatology, 2013
Tetsuji Fujita
openalex   +4 more sources

Clinical Implications of Serum Retinol-Binding Protein 4 in Asthmatic Children

Journal of Korean Medical Science, 2009
Recently the prevalence of both asthma and obesity have increased substantially in many countries. The aim of this study was to evaluate the role of retinol-binding protein (RBP) 4 in childhood asthma and its association with atopy markers, pulmonary function, and bronchial hyperresponsiveness in relation to obesity. We studied 160 children between the
Yeo Hoon Park, Kyung Won Kim, Kyung Eun Lee, Eun Soo Kim, Myung Hyun Sohn, Kyu-Earn Kim   +5 more
openalex   +4 more sources