Results 71 to 80 of about 16,382,176 (245)
Retinol Binding Protein 4 and Fatty Liver: A Direct Link? [PDF]
Hepatology, 2013 Retinol-binding protein 4 (RBP4) is a 21-kDa protein that facilitates the transport of retinol through the circulation to peripheral tissues. The principal source of RBP4 in the body is the liver. Hepatocytes are the primary producers of RBP4; they use the protein to contribute to total-body retinol homeostasis by complexing it with dietary retinol and
openaire +2 more sources
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata +7 more
wiley +1 more source
Retinol-Binding Protein Interferes with Transthyretin-Mediated β‑Amyloid Aggregation Inhibition
, 2018 β-Amyloid (Aβ) aggregation is causally linked to Alzheimer’s disease. On the basis of in vitro and transgenic animal studies, transthyretin (TTR) is hypothesized to provide neuroprotection against Aβ toxicity by binding to Aβ and inhibiting its ...
Regina M. Murphy +3 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundVisceral adipose tissue (VAT) and fatty liver differ in their associations with cardiovascular risk compared with subcutaneous adipose tissue (SAT).
Jane J. Lee +10 more
doaj +1 more source
Serum biomarker panel for the diagnosis of rheumatoid arthritis
Arthritis Research & Therapy, 2021 Background Rheumatoid arthritis (RA) is an autoimmune disease of inflammatory joint damage, wherein C-reactive protein and autoantibodies including rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) are rapidly elevated.
Sora Mun +5 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Clinical significance of acute kidney injury in idiosyncratic drug‐induced liver injury: a multicentric propensity scores matched study. Evidence about the role of acute kidney injury (AKI) in idiosyncratic drug‐induced liver injury (DILI) is still scarce.
José María Pinazo‐Bandera +15 more
wiley +1 more source
Directed evolution and structural analysis of an OB-fold domain towards a specifc binding reagent [PDF]
, 2011 Interactions between proteins are a central concept in biology, and understanding and manipulation of these interactions is key to advancing biological science.
Steemson, John Durand
core
مجلة بغداد للعلومThe prevalence of type 2 diabetes has doubled in recent years due to a defect in insulin production, which can develop to form diabetes complications that affect the kidneys, nerves, and eyes.
Heba Mohammed Hatem +1 more
doaj +1 more source
Journal of Research in Medical Sciences, 2018 Background: Since the increase in some tubular damage biomarkers can be observed at the early stage of diabetic nephropathy, even in the absence of albuminuria, we aimed to investigate if urinary albumin is superior than tubular damage marker, such as ...
Aleksandra Klisic +2 more
doaj +1 more source
Altering retinol binding protein 4 levels in hepatitis C: Inflammation and steatosis matter
Virulence, 2020 Both hepatitis C virus (HCV) infection and retinol-binding protein 4 (RBP4) might contribute to insulin resistance (IR), how RBP4 links to IR in HCV infection remain elusive.
Ming-Ling Chang +5 more
doaj +1 more source