Results 11 to 20 of about 1,758,910 (244)

Retinol tracing within murine neural retina reveals cell type–specific retinol transport and distribution [PDF]

The Journal of Clinical Investigation
11-cis-Retinal is essential for light perception in mammalian photoreceptors (PRs), and aberrations in retinoid transformations cause severe retinal diseases. Understanding these processes is crucial for combating blinding diseases.
Zachary J. Engfer, Grazyna Palczewska, Samuel W. Du, Jianye Zhang, Zhiqian Dong, Carolline Rodrigues Menezes, Jun Wang, Jianming Shao, Budd A. Tucker, Robert F. Mullins, Rui Chen, Philip D. Kiser, Krzysztof Palczewski   +12 more
doaj   +4 more sources

Transport of retinol in the duck plasma [PDF]

Journal of Biosciences, 1981
Retinol-binding protein and prealbumin were isolated from duck plasma by chromatography on DEAE-cellulose-and DEAE-Sephadex A-50, gel filtration on Sephadex G- 100 and preparative Polyacrylamide gel electrophoresis. The molecular weights of the retinolbinding protein-prealbumin complex, prealbumin and retinol-binding protein were found to be 75,000 ...
Sridhara Rao, B, Appaji Rao, N, Cama, HR
openaire   +5 more sources

An ambulance for retinol [PDF]

eLife, 2014
During inflammation, serum amyloid A proteins transport retinol to infected tissues.
Stephanie C Ganal, Andrew J MacPherson
doaj   +3 more sources

Comparative studies of retinol transport in plasma

Journal of Lipid Research, 1973
The comparative immunology and biochemistry of plasma retinol transport were studied using radioimmunoassays previously developed for human and for rat retinol-binding protein (RBP).
Yasutoshi Muto, Frank Rees Smith, DeWitt S. Goodman   +2 more
doaj   +3 more sources

Retinol and Retinol-Binding Protein Stabilize Transthyretin via Formation of Retinol Transport Complex

ACS Chemical Biology, 2010
Transthyretin (TTR) is a plasma hormone carrier protein associated with hereditary and senile forms of systemic amyloid disease, wherein slow tetramer disassembly is thought to be an obligatory step. Plasma transport of retinol is carried out exclusively by the retinol-binding protein (RBP), through complexation with transthyretin.
Hyung, Suk-Joon, Deroo, Stéphanie, Robinson, Carol V   +2 more
openaire   +5 more sources

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

eLife, 2014
Retinol plays a vital role in the immune response to infection, yet proteins that mediate retinol transport during infection have not been identified.
Mehabaw G Derebe, Clare M Zlatkov, Sureka Gattu, Kelly A Ruhn, Shipra Vaishnava, Gretchen E Diehl, John B MacMillan, Noelle S Williams, Lora V Hooper   +8 more
doaj   +3 more sources

Transthyretin and Vitamin A Metabolism: A Review for the Cardiac Amyloidosis Specialist [PDF]

Journal of Cardiovascular Development and Disease
Transthyretin (TTR) amyloidosis is a systemic, progressive, and fatal disease. TTR is integral in vitamin A (retinol) transport via its binding to retinol binding protein 4 (RBP4).
Donclair Brown, Vishakha Modak, Aladin Altic, Ali Al Zuwayny, James Tauras   +4 more
doaj   +2 more sources

Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4) [PDF]

Journal of Biological Chemistry, 2013
Vitamin A (retinol) is absorbed in the small intestine, stored in liver, and secreted into circulation bound to serum retinol-binding protein (RBP4). Circulating retinol may be taken up by extrahepatic tissues or recycled back to liver multiple times before it is finally metabolized or degraded.
Brandon Bacon, Ashot Sargsyan, Fangjian Guo   +2 more
exaly   +3 more sources

Maternal obesity remodels nutrient transport transcriptional programs in early mouse embryonic and extraembryonic cell lineages [PDF]

Molecular Metabolism
Background: Maternal obesity increases the risk of congenital anomalies and later-life metabolic disease in offspring. Still, underlying mechanisms remain unclear, particularly in extraembryonic lineages at the maternal–fetal interface, which remain ...
Amalia Caballero, Lijun Chi, Paul Delgado-Olguín   +2 more
doaj   +2 more sources

Real-time analyses of retinol transport by the membrane receptor of plasma retinol binding protein. [PDF]

J Vis Exp, 2013
Vitamin A is essential for vision and the growth/differentiation of almost all human organs. Plasma retinol binding protein (RBP) is the principle and specific carrier of vitamin A in the blood. Here we describe an optimized technique to produce and purify holo-RBP and two real-time monitoring techniques to study the transport of vitamin A by the high ...
Kawaguchi R, Zhong M, Sun H.
europepmc   +4 more sources