Results 81 to 90 of about 15,860 (203)

The role of extrahepatic retinol binding protein in the mobilization of retinoid stores

open access: yesJournal of Lipid Research, 2004
Although the major tissue site of retinol binding protein (RBP) synthesis in the body is the liver, other sites of synthesis have been reported. The physiological role(s) of circulating RBP that is produced and secreted extrahepatically has not been ...
Loredana Quadro   +7 more
doaj   +1 more source

Causal Effects of Type 2 Diabetes Mellitus on Chronic Periodontitis and the Mediating Role of Oxidative Stress: Evidence From Mendelian Randomization and Mediation Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Type 2 diabetes mellitus (T2DM) is associated with an increased risk of chronic periodontitis, but genetic evidence and oxidative stress‐related pathways remain unclear. Objective This study assessed the genetically inferred association between T2DM and chronic periodontitis, evaluated oxidative stress biomarkers as potential ...
Mengjie Kong   +3 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Alterations to oxidative stress markers in dogs after a short-term stress during transport*

open access: yesJournal of Nutritional Science, 2014
While methods to evaluate antioxidant capacity in animals exist, one problem with the models is induction of oxidative stress. It is necessary to promote a great enough challenge to induce measurable alterations to oxidative parameters while ensuring the
Chayanne S. Ferreira   +8 more
doaj   +1 more source

Sustainable replacement of fishmeal with Artemia biomass in diets for Nile tilapia (Oreochromis niloticus)

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
ABSTRACT This study evaluated the effects of substituting fishmeal with Artemia biomass in aquaculture diets on growth performance and whole‐body composition of Nile tilapia (Oreochromis niloticus). Four dietary treatments were administered in triplicate to juvenile Nile tilapia (44 g) stocked in 1m3 cages in a pond at 30 fish per cage for 84 days. The
Mary A. Opiyo   +6 more
wiley   +1 more source

Short‐Term Effect of Fishmeal‐Free Feed Formulation on Growth Performance, Feed Efficiency and Transcriptomic Profile of Hypothalamus and Liver in Atlantic Salmon

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
Transcriptomic responses of the hypothalamus and liver were compared in Atlantic salmon fed fishmeal or fishmeal‐free diets under simulated Tasmanian summer conditions. Fishmeal‐free feeding reduced growth performance, downregulated hypothalamic orexigenic pathways and increased hepatic lipogenesis. ABSTRACT Atlantic salmon (Salmo salar) aquaculture is
Maximiliano M. Canepa   +6 more
wiley   +1 more source

Structural and binding properties of two paralogous fatty acid binding proteins of Taenia solium metacestode.

open access: yesPLoS Neglected Tropical Diseases, 2012
BackgroundFatty acid (FA) binding proteins (FABPs) of helminths are implicated in acquisition and utilization of host-derived hydrophobic substances, as well as in signaling and cellular interactions. We previously demonstrated that secretory hydrophobic
Seon-Hee Kim   +7 more
doaj   +1 more source

Acute Kidney Injury Remodels Hepatic Iron Handling and Depletes Glutathione Defense in the Mouse Liver

open access: yesComprehensive Physiology, Volume 16, Issue 6, December 2026.
Acute kidney injury recruits the liver into an IL‐6/STAT3 acute‐phase program whose iron‐withholding arm runs while glutathione defense collapses and tetrahydrobiopterin biosynthetic capacity falls; total hepatic iron decreases and ferrous‐reactive iron is unchanged.
Minghua Li   +6 more
wiley   +1 more source

Plasma retinol transport and clearance in hypervitaminosis A.

open access: yesJournal of dairy science, 1979
Effects of mild and severe hypervitaminosis A on retinol transport and clearance were studied in mature ewes. Excessive vitamin A intake was assoicated with high concentrations of vitamin A in plasma and liver, with elevated serum enzymes, with decreased feed consumption and packed cell volume, and with epithelial hyperplasia.
S, Donoghue, D S, Kronfeld, C F, Ramberg
openaire   +1 more source

Single‐Cell Integration of Mouse Models of Autism Reveals Conserved Transcriptomic Signatures of Excitatory‐Inhibitory Imbalance and Glial Dysfunction

open access: yesGlia, Volume 74, Issue 12, December 2026.
Integrated scRNA‐seq from 11 ASD models reveals convergent E/I imbalance and glial dysfunction. Conserved astrocyte and oligodendrocyte dysregulation transcend model‐specific variability. Validated by human datasets. ABSTRACT The etiological heterogeneity of autism spectrum disorder (ASD) complicates identifying core molecular mechanisms.
João V. Nani   +3 more
wiley   +1 more source

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