Results 81 to 90 of about 15,495 (243)
Structural and functional characterization of the retinol-binding protein receptor STRA6
, 2021 Vitamin A is an essential nutrient; it is not synthesized by mammals and therefore must be obtained through the diet. During times of fasting or dietary vitamin A insufficiency, retinol, the alcohol form of the vitamin is released from the liver, its ...
Costabile, Brianna Kay
core +2 more sources
Frontiers in Cell and Developmental BiologyRetinol-binding protein 4 (RBP4) has emerged as a critical adipokine involved in the pathophysiology of metabolic and cardiovascular diseases. Beyond its classical role in retinol transport, RBP4 influences insulin resistance, inflammation, lipid ...
Kangzhen Zhang +3 more
doaj +1 more source
Metabolism of retinol-binding protein and vitamin A during hypervitaminosis A in the rat
Journal of Lipid Research, 1975 Vitamin A is normally transported in plasma as retinol bound to a specific protein, retinol-binding protein (RBP). Detailed studies were conducted to examine the effects of excess vitamin A on the plasma concentration and metabolism of RBP, and to obtain
A.K. Mallia, J.E. Smith, D.W. Goodman
doaj +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley +1 more source
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Carence en vitamine A chez les bovins : étude bibliographique et clinique [PDF]
, 2009 La vitamine A est un élément très important pour l'organisme des bovins. Elle intervient dans de nombreuses fonctions essentielles comme la vision, les épithéliums, l'immunité, le développement et la croissance, les phénomènes de détoxification ou la ...
Yervant, Marie
core
, 1989 Serum retinol-binding protein (RBP) is believed to be responsible for the transport of retinol from its storage site in the liver to vitamin A requiring target cells such as keratinocytes.
Silverman-Jones, Carol S. +2 more
core +1 more source
Alterations to oxidative stress markers in dogs after a short-term stress during transport*
Journal of Nutritional Science, 2014 While methods to evaluate antioxidant capacity in animals exist, one problem with the models is induction of oxidative stress. It is necessary to promote a great enough challenge to induce measurable alterations to oxidative parameters while ensuring the
Chayanne S. Ferreira +8 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
Molecular basis for retinol binding by serum amyloid A during infection
, 2019 Serum amyloid A (SAA) proteins are strongly induced in the liver by systemic infection and in the intestine by bacterial colonization. In infected mice, SAA proteins circulate in association with the vitamin A derivative retinol, suggesting that SAAs ...
Hu, Zehan +3 more
core +1 more source