Results 91 to 100 of about 15,860 (203)
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso +8 more
wiley +1 more source
Structural and biochemical basis for retinol‐binding protein 4 antagonism by tinlarebant
Background and Purpose Retinol‐binding protein 4 (RBP4) is a member of the lipocalin superfamily that is connected to disease states such as insulin resistance, fatty liver disease and ocular disorders including Stargardt disease. Several retinoid and non‐retinoid antagonists of this protein have been developed for potential clinical use, but none have
Marco Bassetto, Philip D. Kiser
wiley +1 more source
Regulation of IL‐13 Signaling by Retinoic Acid in Airway Epithelial Cells
Our proteomics and subsequent biochemical analyses reveal the effects of retinoic acid receptor (RAR) agonists, ATRA (pan‐RAR agonist), or CD1530 (RARγ agonist) in counteracting molecular changes induced by IL‐13 relevant to airway inflammation and remodeling, such as proteins involved in epithelial‐to‐mesenchymal transition (EMT) and extracellular ...
Vanshika Patel +5 more
wiley +1 more source
Abstract Background Research into disorders in captive reptiles is notably sparse in the UK, despite the popularity of various species as pets. This study aimed to survey and investigate risk factors for disorders of leopard geckos in the UK. Methods Medical records for leopard geckos presenting at three veterinary practices between 2019 and 2023 were ...
Joshua Henley, Tom Dutton, Joanna Hedley
wiley +1 more source
Background: Cardiometabolic disorders, notably primary hypertension and type 2 diabetes, present substantial global health challenges. The intricate interplay between metabolic and cardiovascular pathways has prompted extensive research into molecular ...
Anand G. Jadhao +2 more
doaj +1 more source
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata +7 more
wiley +1 more source
ABSTRACT Ulcerative colitis (UC) and depression (DP) are significant comorbidities in epidemiological research. However, the mechanisms underlying UC‐induced DP remain poorly understood. Myeloid differentiation and retinoic acid metabolic dysregulation are implicated in both conditions, yet their interconnection in the context of comorbidity is unclear.
Yang Feng +7 more
wiley +1 more source
Nutrient adequacy depends on food composition, bioaccessibility, absorption, physiological utilization, dietary access, supply stability, etc. Food properties, human health, agricultural conditions, and socioeconomic barriers influence nutrient delivery.
Chinaza Godswill Awuchi
wiley +1 more source
The study assessed the demographic and nutritional profiles of children aged 2–5 years with and without thalassemia carrier status in Belkuchi, Sirajganj, Bangladesh. Thalassemia carrier children had significantly lower height‐for‐age z‐scores (HAZ), indicating poorer linear growth.
Sabuktagin Rahman +3 more
wiley +1 more source
Oviductus Ranae protein hydrolysate (ORPH) ameliorates CUMS‐induced depressive‐like behaviors in mice, accompanied by altered gut microbiota and tryptophan/sphingolipid metabolism. ABSTRACT Depression constitutes a significant global health burden, manifesting as persistent low mood, anhedonia, and behavioral disturbances.
Mengmeng Liu +7 more
wiley +1 more source

