Results 191 to 200 of about 36,775 (295)

Synchronous Faithfulness Monitoring for Trustworthy Retrieval-Augmented Generation

Retrieval-augmented language models (RALMs) have shown strong performance and wide applicability in knowledge-intensive tasks. However, there are significant trustworthiness concerns as RALMs are prone to generating unfaithful outputs, including baseless
Gu, Jia-Chen, Yin, Fan, Peng, Nanyun, Wu, Di, Chang, Kai-Wei   +4 more
core  

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

ChatTogoVar: a TogoVar-based retrieval-augmented generation system for precise genomic variant interpretation. [PDF]

Hum Genome Var
Mitsuhashi N, Fujiwara T, Yamaguchi A.
europepmc   +1 more source

Система керування документацією з використанням «Retrieval Augmented Generation»

В магістерської дисертації розглядається використання Retrieval Augmented Generation на прикладі системи керування документацією. Як практична сторона реалізований програмний продукт, що використовує RAG та великі мовні моделі для поліпшення ...
Красновський, Олексій Володимирович
core  

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Low-energy small language models with retrieval-augmented generation can surpass large-model performance in rheumatology. [PDF]

Front Med (Lausanne)
Felde S, Buchkremer R, Chehab G, Thielscher C, Distler JHW, Schneider M, Richter JG.   +6 more
europepmc   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

Advanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang, Shibo Zhao, Wenying Wu, Zhiwei Duan, Yuan Li, Xiangyu Zeng, Liang Hong, Yan Chen, Ling Tao, Kewu Zeng, Chaoda Xiao, Xiangchun Shen   +11 more
wiley   +1 more source

MedDiscover: A Domain-Specific Retrieval-Augmented Generation Framework for Evidence-Grounded Knowledge Extraction in Metabolomics. [PDF]

Comput Struct Biotechnol J
Patel VP, Jolkver E, Schwerk A.
europepmc   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Enhancing adversarial resilience in semantic caching for secure retrieval augmented generation systems. [PDF]

Sci Rep
Afiffy M, Fakhr MW, Maghraby FA.
europepmc   +1 more source