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Reduced Peroxisomal Import Triggers Peroxisomal Retrograde Signaling

open access: yesCell Reports, 2021
Maintaining organelle function in the face of stress is known to involve organelle-specific retrograde signaling. Using Caenorhabditis elegans, we present evidence of the existence of such retrograde signaling for peroxisomes, which we define as the ...
Jonathan J. Ewbank   +2 more
exaly   +2 more sources
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Mitochondrial Retrograde Signaling

Annual Review of Genetics, 2006
Mitochondrial retrograde signaling is a pathway of communication from mitochondria to the nucleus under normal and pathophysiological conditions. The best understood of such pathways is retrograde signaling in the budding yeast Saccharomyces cerevisiae.
Zhengchang Liu, Ronald A Butow
exaly   +3 more sources

Retrograde Signaling by Endocannabinoids

Current Opinion in Neurobiology, 2002
Recent studies suggest that endocannabinoids act as retrograde messengers at many synapses in the central nervous system. Activation of phospholipases, either through calcium-mediated or receptor-mediated signaling, leads to the formation and release of endocannabinoids. These lipophilic signaling molecules diffuse to nearby presynaptic terminals where
Anatol C Kreitzer, Wade Regehr
exaly   +3 more sources

Retrograde signaling in axonal regeneration

Experimental Neurology, 2010
Neuronal regeneration in the peripheral nervous system requires mobilization of intrinsic neurite outgrowth mechanisms. This process depends on retrograde signaling between lesion site and soma to provide accurate and timely information on the nature and extent of axonal damage, and to elicit an appropriate cell body response.
Ida, Rishal, Mike, Fainzilber
openaire   +2 more sources

The Retrograde Signaling Protein GUN1 Regulates Tetrapyrrole Biosynthesis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
The biogenesis of the photosynthetic apparatus in developing seedlings requires the assembly of proteins encoded on both nuclear and chloroplast genomes.
Matthew Terry   +2 more
exaly   +2 more sources

Retrograde Signalling by Endocannabinoids

2005
The cannabinoid neurotransmitter system comprises cannabinoid G protein-coupled membrane receptors (CB1 and CB2), endogenous cannabinoids (endocannabinoids), as well as mechanisms for their synthesis, membrane transport and metabolism. Within the brain the marijuana constituent delta9-tetrahydrocannabinol (THC) produces its pharmacological actions by ...
C W, Vaughan, M J, Christie
openaire   +2 more sources

PLASTID-TO-NUCLEUS RETROGRADE SIGNALING

Annual Review of Plant Biology, 2006
Plant cells store genetic information in the genomes of three organelles: the nucleus, plastid, and mitochondrion. The nucleus controls most aspects of organelle gene expression, development, and function. In return, organelles send signals to the nucleus to control nuclear gene expression, a process called retrograde signaling.
Ajit, Nott   +3 more
openaire   +2 more sources

Emerging Trends in Retrograde Signaling

Molecular Neurobiology, 2015
Retrograde signaling is defined as the signaling events leading from the plastids to the nucleus in plants and across the chemical synapse, from the postsynaptic neuron to the presynaptic neuron in animals. The discovery of various retrograde messengers has opened many avenues and clouds of thoughts as to the role of retrograde signaling.
Yashasvi, Suvarna   +2 more
openaire   +2 more sources

Functions and mechanisms of retrograde neurotrophin signalling

Nature Reviews Neuroscience, 2005
Neuronal connections are established and refined through a series of developmental programs that involve axon and dendrite specification, process growth, target innervation, cell death and synaptogenesis. Many of these developmental events are regulated by target-derived neurotrophins and their receptors, which signal retrogradely over long distances ...
Larry S, Zweifel   +2 more
openaire   +2 more sources

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