Results 141 to 150 of about 50,812 (253)
R2Tg retrotransposon mediated targeted integration of exogenous genes into the 28S rDNA locus in mammalian cell lines for PKU gene therapy [PDF]
Xiuyuan Wang +8 more
openalex +1 more source
Abstract Horizontal gene transfer (HGT) can accelerate plant adaptation, but the evolutionary fate of newly acquired nuclear genes is often unclear. Here, we analyzed a papain‐like cysteine peptidase horizontally transferred from Panicoideae to wild Hordeum (Poaceae). Using chromosome‐level assemblies of 21 diploid Hordeum species, we assessed presence/
Václav Mahelka +9 more
wiley +1 more source
High‐density mutation tracks are associated with proton‐beam irradiation patterns in Sorghum bicolor
Abstract Induced mutagenesis is a cornerstone of crop functional genomics, yet the extent to which distinct radiation sources reshape the spatial distribution of mutations remains difficult to evaluate in reduced‐representation datasets. Here, we analyze a published genotyping‐by‐sequencing (GBS) panel (192,040 loci) to compare proton‐beam and gamma ...
Ezekiel Ahn +6 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ziyi Ouyang, Hongqing Liang, Dan Zhang
wiley +1 more source
Molecular insights and translational opportunities to enhance heat tolerance in rice
Abstract Heat stress is an increasingly serious threat to rice (Oryza sativa L.) productivity, yet the genetic and regulatory architecture underlying thermotolerance remain poorly resolved and fragmented across studies. Earlier research focused on individual pathways or specific developmental stages; however, recent advances now support an integrated ...
Prabhat Rana +7 more
wiley +1 more source
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang +6 more
wiley +1 more source
Abstract Fusarium head blight (FHB) is a devastating disease that severely impacts global wheat (Triticum aestivum L.) production. Sumai 3, a wheat cultivar widely used in breeding programs for its strong FHB resistance, has not been fully resolved at the chromosome level.
Rubylyn D. Mijan +10 more
wiley +1 more source
Abstract Callery pear (Pyrus calleryana) is a deciduous species native to East Asia with notable ornamental and ecological value, but the genomic resources for this species remain limited. Here, we report the first haplotype‐resolved, chromosome‐scale genome of P. calleryana.
Xiaogang Dai +9 more
wiley +1 more source
Abstract Barley (Hordeum vulgare L.) is an important crop in the world, and its seed dormancy is primarily controlled by a mitogen‐activated protein kinase kinase 3 (MKK3) gene. Although kinase activity of MKK3 and its roles in barley post‐domestication have been widely studied, the pre‐domestication evolution of MKK3 and the spread of nondormant ...
Lydia G. Tressel +3 more
wiley +1 more source

