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Yeast retrotransposons and tRNAs

Trends in Genetics, 1993
The role of tRNAs in protein synthesis seems routine when compared with the novel ways in which the Ty retrotransposons of Saccharomyces cerevisiae use these interpreters of the genetic code. tRNAs and tRNA genes control essential steps in the retrotransposon life cycle by regulating protein expression, priming DNA synthesis and specifying integration ...
D F, Voytas, J D, Boeke
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Retrotransposons and regulatory suites

BioEssays, 2005
Cellular differentiation and multicellular development require the programmed expression of coregulated suites of genetic loci dispersed throughout the genome. How do functionally diverse loci come to share common regulatory motifs? A new paper finds that retrotransposons (RTEs) may play a role in providing common regulation to a group of functions ...
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Retrotransposon replication in plants

Current Opinion in Virology, 2013
Retrotransposons comprise the bulk of large plant genomes, replicating via an RNA intermediate whereby the original, integrated element remains in place. Of the two main orders, the LTR retrotransposons considerably outnumber the LINEs. LINEs integrate into target sites simultaneously with the RNA transcript being copied into cDNA by target-primed ...
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Sex and retrotransposons

Trends in Microbiology, 2001
Transposable genetic elements (TGEs) produce major deleterious effects in the host organism yet they still spread through the populations of sexually reproducing organisms. TGEs can become established in sexual populations because sexual reproduction allows them to go to fixation if the reduction in fitness of the host is less than twofold.
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Drosophila Retrotransposons: Interactions With Genome

1989
Publisher Summary The “dogma” of the fixity of the genome, as it was defined in the 1920s based on Morgan's chromosomal theory of heredity and according to which every gene occupies a definite location along a specific chromosome with the rare exceptions of accidental translocations, has been seriously questioned since B.
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