Results 51 to 60 of about 67,814 (281)
An age-of-allele test of neutrality for transposable element insertions [PDF]
, 2013 How natural selection acts to limit the proliferation of transposable elements (TEs) in genomes has been of interest to evolutionary biologists for many years.
Bergman, Casey M. +3 more
core +2 more sources
Current Opinion in Genetics & Development, 1992 In the decade since Ty elements were discovered, advocates have argued they could be used as a genetic entrée to elusive host-type functions required by retroviruses. However, the advent of the polymerase chain reaction, coupled with a boom in funding for human immunodeficiency virus research have moved retroviral research apace, raising questions as ...
openaire +4 more sources
Regulation of rice root development by a retrotransposon acting as a microRNA sponge
eLife, 2017 It is well documented that transposable elements (TEs) can regulate the expression of neighbouring genes. However, their ability to act in trans and influence ectopic loci has been reported rarely.
Jungnam Cho, J. Paszkowski
semanticscholar +1 more source
TUT-TUTting retrotransposons [PDF]
Nature Reviews Molecular Cell Biology, 2018 3′uridylation by TUT4 and TUT7 is shown as a post-transcriptional mechanism restricting retrotransposition of LINE-1 elements and also replication of animal RNA viruses.
openaire +2 more sources
Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing [PDF]
, 2014 Retrotransposons constitute a major source of genetic variation, and somatic retrotransposon insertions have been reported in cancer. Here, we applied TranspoSeq, a computational framework that identifies retrotransposon insertions from sequencing data ...
Getz, Gad +5 more
core +1 more source
Sequencing the extrachromosomal circular mobilome reveals retrotransposon activity in plants
PLoS Genetics, 2017 Retrotransposons are mobile genetic elements abundant in plant and animal genomes. While efficiently silenced by the epigenetic machinery, they can be reactivated upon stress or during development.
Sophie Lanciano +8 more
semanticscholar +1 more source
LTRs of Endogenous Retroviruses as a Source of Tbx6 Binding Sites
Frontiers in Chemistry, 2017 Retrotransposons are abundant in mammalian genomes and can modulate the gene expression of surrounding genes by disrupting endogenous binding sites for transcription factors (TFs) or providing novel TFs binding sites within retrotransposon sequences ...
Yukuto Yasuhiko +2 more
doaj +1 more source
Cell division promotes efficient retrotransposition in a stable L1 reporter cell line [PDF]
, 2013 Background: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the ...
An, Wenfeng +5 more
core +2 more sources
Retrotransposon Domain Swapping [PDF]
The Plant Cell, 2010 Whether you consider them major genomic parasites or potentially major drivers of genome expansion, long terminal repeat (LTR) retrotransposons are major, making up 15 to 90% of plant nuclear genomes (reviewed in Sabot and Schulman, 2006). These elements transpose by a replicate-and-paste mechanism, wherein an RNA copy of the retrotransposon is reverse
openaire +2 more sources
Distribution and conservation of the transposable element gypsy in drosophilid species
Genetics and Molecular Biology, 2007 In an attempt to understand the dynamics of transposable elements (T'S) in the genome of host species, we investigated the distribution, representativeness and conservation of DNA sequences homologous to the Drosophila melanogaster gypsy retrotransposon ...
Fabiana Herédia +2 more
doaj +1 more source