Results 61 to 70 of about 55,792 (268)

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye   +5 more
wiley   +1 more source

Reverse Mutations in Pigmentation Induced by Sodium Azide in the IR64 Rice Variety

open access: yesCurrent Issues in Molecular Biology
Pigmentation in rice is due mainly to the accumulation of anthocyanins. Five color mutant lines, AZ1701, AZ1702, AZ1711, AZ1714, and AZ1715, derived from the sodium azide mutagenesis on the non-pigmented IR64 variety, were applied to study inheritance ...
Hsian-Jun Chen   +6 more
doaj   +1 more source

Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells

open access: yeseLife, 2017
Mobilization of retrotransposons to new genomic locations is a significant driver of mammalian genome evolution, but these mutagenic events can also cause genetic disorders.
Marie MacLennan   +17 more
doaj   +1 more source

Processing of insect retrotransposons by self-cleaving ribozymes [PDF]

open access: yes, 2010
We show that several classes of insect non-LTR retrotransposons harbor self-cleaving ribozymes of the HDV family at their 5′ termini. In Drosophila the R2 ribozymes exhibit highly differential in vivo expression and robust in vitro activity ...
Andrej Luptak   +3 more
core   +1 more source

The Imprinted Retrotransposon-Like Gene PEG11 (RTL1) Is Expressed as a Full-Length Protein in Skeletal Muscle from Callipyge Sheep [PDF]

open access: yes
peer-reviewedMembers of the Ty3-Gypsy retrotransposon family are rare in mammalian genomes despite their abundance in invertebrates and some vertebrates.
Bidwell, Christopher A.   +8 more
core   +1 more source

Molecular mechanisms of sex determination in Lepidoptera: current status and perspectives

open access: yesInsect Science, EarlyView.
The genetic basis of sex determination in Lepidoptera was discovered in 2014 in the silkworm Bombyx mori. In this model species, the W chromosome‐derived small piRNA called Fem piRNA downregulates the expression of a Z‐linked gene, Masculinizer (Masc), which leads to the default female‐specific splicing of the doublesex gene (dsxF) and thus to female ...
František Marec   +2 more
wiley   +1 more source

LTR Retrotransposons in Fungi

open access: yesPLoS ONE, 2011
Transposable elements with long terminal direct repeats (LTR TEs) are one of the best studied groups of mobile elements. They are ubiquitous elements present in almost all eukaryotic genomes. Their number and state of conservation can be a highlight of genome dynamics.
Anna Muszewska   +2 more
openaire   +4 more sources

Chromosome‐Level Genome Assemblies of Two Softshell Turtles with ZZ/ZW Provide Insights into TE‐Driven Recombination Suppression in Sex Chromosomes

open access: yesIntegrative Zoology, EarlyView.
This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu   +9 more
wiley   +1 more source

Transposable Elements, Inflammation, and Neurological Disease. [PDF]

open access: yes, 2019
Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela   +2 more
core  

Single-molecule real-time sequencing combined with optical mapping yields completely finished fungal genome [PDF]

open access: yes, 2015
Next-generation sequencing (NGS) technologies have increased the scalability, speed, and resolution of genomic sequencing and, thus, have revolutionized genomic studies.
Datema, Erwin   +6 more
core   +2 more sources

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