Results 21 to 30 of about 165,526 (354)

HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models

Frontiers in Immunology, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is the causative infectious agent of adult T-cell leukemia/lymphoma (ATL) and chronic neurological disease.
Victoria Maksimova, Susan Smith, Jaideep Seth, Cameron Phelps, Stefan Niewiesk, Yorifumi Satou, Patrick L. Green, Patrick L. Green, Amanda R. Panfil, Amanda R. Panfil   +9 more
doaj   +1 more source

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate [PDF]

, 2015
During the late stages of the HIV-1 replication cycle, the viral polyprotein Pr55Gag is recruited to the plasma membrane (PM), where it binds phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and directs HIV-1 assembly.
Balasubramaniam, Balla, Benaroch, Bennett, Berditchevski, Blott, Booth, Buchacher, Bussolino, Carolina Jancic, Carr, Catalina von Bilderling, Catarina Ferreira Moita, Checkley, Chen, Chesebro, Chu, Claudia Banchio, Cox, Deneka, Desnos, Dimitrov, Dong, Doughman, Eric O. Freed, Gabriel Duette, Genevieve de Saint Basile, Gould, Grigorov, Guo, Hammond, Hogue, Hume, Imai, Jolly, Jolly, Jorge Geffner, Joshi, Jouve, Jović, Kang, Kerviel, Krementsov, Krementsov, Li, Lloyd, Lorena Sigaut, Luciana Paoletti, Luis Ferreira Moita, Lía I. Pietrasanta, Manders, Matías Ostrowski, Mercedes Cabrini, Micucci, Minogue, Mlcochova, Moffat, Monde, Ménasché, Ménasché, Nakatsu, Naldini, Ono, Ostrowski, Pan, Pehuén Pereyra Gerber, Philippe Benaroch, Pizarro-Cerdá, Popovic, Raposo, Raposo, Ruiz-Mateos, Salazar, Satoh, Schindler, Sebastian Amigorena, Sibarita, Sundquist, Théry, Trkola, Tsuboi, Tsuboi, Vickers, Villalta, Várnai, Wang, Wei, Welsch, Yauch   +88 more
core   +1 more source

HLA-B*35 as a new marker for susceptibility to human T-cell lymphotropic virus type 1 (HTLV-1) Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in patients living in Argentina

Retrovirology, 2020
Background Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV associated myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) and Adult T cell leukemia/lymphoma (ATLL), in around 2–5% of the infected individuals.
Paula Benencio, Sindy A. Fraile Gonzalez, Nicolás Ducasa, Kimberly Page, Carolina A. Berini, Mirna M. Biglione   +5 more
doaj   +1 more source

Chronic adult T-cell Leukemia in a young male after blood transfusion as a newborn [PDF]

, 2016
Human T-cell Lymphotropic virus type 1 (HTLV-1) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HTM/TSP).
Altube, Alejandra, Berini, Carolina Andrea, Biglione, Mirna Marcela, Cabral Lorenzo, María Cecilia, Colucci, Magalí, Cánepa, Camila, Deves, Alberto, Halperin, Nora Silvia, Hermine, Olivier, Rojas, Francisca, Ruggieri, Matias   +10 more
core   +2 more sources

Betaretrovirus infections in dromedary camels in Saudi Arabia

Veterinary Medicine and Science, 2022
Background Retroviral infections have been reported in many species of animals, especially cattle, sheep and goats. However, there are no available reports about retrovirus infection in dromedary camels. Several dromedary camels showed visible tumor‐like
Maged Gomaa Hemida, Abdelmohsen A. Alnaeem   +1 more
doaj   +1 more source

Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi [PDF]

, 2017
The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation
Burgos, Juan Miguel, Leguizamon, Maria Susana, Ojeda, Diego Sebastian, Pascuale, Carla Antonela, Quarleri, Jorge Fabian, Urquiza, Javier Mariano   +5 more
core   +1 more source

HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo

Retrovirology, 2019
Background Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Michael P. Martinez, Xiaogang Cheng, Ancy Joseph, Jacob Al-Saleem, Amanda R. Panfil, Marilly Palettas, Wessel P. Dirksen, Lee Ratner, Patrick L. Green   +8 more
doaj   +1 more source

Biological evaluation and molecular modelling of didanosine derivatives [PDF]

, 2014
Five carbonate derivatives of 50-O-20,30-dideoxyinosine (DDI, 1) have been synthesized by combination with aliphatic alcohols, with their in vitro anti-HIV activity and cytotoxicity being evaluated afterward in human peripheral blood mononuclear cells ...
Briñon, Margarita Cristina, de Candia, Cristian Ariel, Gualdesi, María Soledad, Pampuro, Sandra Esther, Quevedo, Mario Alfredo, Ravetti, Soledad, Turk, Gabriela Julia Ana   +6 more
core   +1 more source

Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma

Antioxidants, 2023
Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers.
Piyanard Boonnate, Ryusho Kariya, Seiji Okada   +2 more
doaj   +1 more source

Progress, challenges, and responsibilities in retrovirology [PDF]

, 2005
In this editorial, Retrovirology's choice for best basic science "retrovirus paper of the year" and a perspective on challenges and responsibilities facing HIV-1 and HTLV-I research are ...
Jeang, Kuan-Teh
core   +3 more sources