Results 21 to 30 of about 157,125 (279)

Betaretrovirus infections in dromedary camels in Saudi Arabia

Veterinary Medicine and Science, 2022
Background Retroviral infections have been reported in many species of animals, especially cattle, sheep and goats. However, there are no available reports about retrovirus infection in dromedary camels. Several dromedary camels showed visible tumor‐like
Maged Gomaa Hemida, Abdelmohsen A. Alnaeem   +1 more
doaj   +1 more source

HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models

Frontiers in Immunology, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is the causative infectious agent of adult T-cell leukemia/lymphoma (ATL) and chronic neurological disease.
Victoria Maksimova, Susan Smith, Jaideep Seth, Cameron Phelps, Stefan Niewiesk, Yorifumi Satou, Patrick L. Green, Patrick L. Green, Amanda R. Panfil, Amanda R. Panfil   +9 more
doaj   +1 more source

Distribution, diversity and evolution of endogenous retroviruses in perissodactyl genomes [PDF]

, 2018
The evolution of mammalian genomes has been shaped by interactions with endogenous retroviruses (ERVs). In this study, we investigated the distribution and diversity of ERVs in the mammalian order Perissodactyla, with a view to understanding their impact
Gifford, Robert, Murcia, Pablo Ramiro, Zhu, Henan   +2 more
core   +1 more source

Identification and characterization of a novel enhancer in the HTLV-1 proviral genome

Nature Communications, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active antisense transcription from the proviral genome. Here, Matsuo et al.
Misaki Matsuo, Takaharu Ueno, Kazuaki Monde, Kenji Sugata, Benjy Jek Yang Tan, Akhinur Rahman, Paola Miyazato, Kyosuke Uchiyama, Saiful Islam, Hiroo Katsuya, Shinsuke Nakajima, Masahito Tokunaga, Kisato Nosaka, Hiroyuki Hata, Atae Utsunomiya, Jun-ichi Fujisawa, Yorifumi Satou   +16 more
doaj   +1 more source

Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma

Antioxidants, 2023
Adult T cell leukemia/lymphoma (ATLL) is an aggressive T-cell malignancy that develops in some elderly human T-cell leukemia virus (HTVL-1) carriers.
Piyanard Boonnate, Ryusho Kariya, Seiji Okada   +2 more
doaj   +1 more source

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide. [PDF]

, 2016
Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in ...
Angelastro, James, Arias, Angelo, Cates, Charles, Cayanan, Geraldine, Fung, Jennifer, Greene, Lloyd, Karpel-Massler, Georg, Lamé, Michael, Nakayama Wong, Lynn, Rowland, Douglas, Sidorov, Maxim, Siegelin, Markus   +11 more
core   +2 more sources

Selection of functional human antibodies from retroviral display libraries [PDF]

, 2004
Antibody library technology represents a powerful tool for the discovery and design of antibodies with high affinity and specificity for their targets.
Urban, Johannes H., Schneider, Richard M., Compte, Marta, Finger, Carsten, Cichutek, Klaus, Álvarez-Vallina, Luis, Buchholz, Christian   +6 more
core   +2 more sources

Childhood sexual experiences with an older partner among men who have sex with men in Buenos Aires, Argentina [PDF]

, 2013
This study sought to describe childhood sexual experiences with older partners (CSEOP) among men who have sex with men (MSM) in Buenos Aires, Argentina. MSM were recruited through respondent driven sampling. They responded to a computer administered self-
Balán, Iván C., Barreda, Victoria, Carballo Diéguez, A., Dolezal, Curtis, Mabragaña, Marina, Marone, Ruben, Pando, María de los Ángeles, Ávila, María Mercedes   +7 more
core   +1 more source

HIV Env conserved element DNA vaccine alters immunodominance in macaques

Human Vaccines & Immunotherapeutics, 2017
Sequence diversity and immunodominance are major obstacles in the design of an effective vaccine against HIV. HIV Env is a highly-glycosylated protein composed of ‘conserved’ and ‘variable’ regions.
Xintao Hu, Antonio Valentin, Margherita Rosati, Siriphan Manocheewa, Candido Alicea, Bhabadeb Chowdhury, Jenifer Bear, Kate E. Broderick, Niranjan Y. Sardesai, Sylvie Le Gall, James I. Mullins, George N. Pavlakis, Barbara K. Felber   +12 more
doaj   +1 more source

Low Proviral Load is Associated with Indeterminate Western Blot Patterns in Human T-Cell Lymphotropic Virus Type 1 Infected Individuals: Could Punctual Mutations be Related?

Viruses, 2015
Background: indeterminate Western blot (WB) patterns are a major concern for diagnosis of human T-cell lymphotropic virus type 1 (HTLV-1) infection, even in non-endemic areas.
Camila Cánepa, Jimena Salido, Matías Ruggieri, Sindy Fraile, Gabriela Pataccini, Carolina Berini, Mirna Biglione   +6 more
doaj   +1 more source