Results 21 to 30 of about 134,326 (264)

Human Endogenous Retrovirus K (HML-2) in Health and Disease

Frontiers in Microbiology, 2020
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections in the evolution of primates and account for about 8% of the human genome.
Bei Xue, L. Sechi, D. Kelvin
semanticscholar   +1 more source

Phenotypic and Genotypic Co-receptor Tropism Testing in HIV-1 Epidemic Region of Tanzania Where Multiple Non-B Subtypes Co-circulate

Frontiers in Microbiology, 2021
HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important.
George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Toong Seng Tan, Seiya Ozono, Amina Shaban Mgunya, Takeo Kuwata, Shuzo Matsushita, Bruno Sunguya, Bruno Sunguya, Eligius Lyamuya, Eligius Lyamuya, Kenzo Tokunaga, Kenzo Tokunaga, Takamasa Ueno, Takamasa Ueno   +16 more
doaj   +1 more source

Death and the retrovirus

Trends in Molecular Medicine, 2003
A flurry of new papers has shown that HIV reverse transcription is vulnerable to G-->A hypermutation. Apparently, cytidine bases in nascent DNA synthesis are lethally edited by the host cell molecule apolipoprotein B editing complex protein (APOBEC) 3G.
Vartanian, Jean Pierre, Sommer, Peter, Wain-Hobson, Simon   +2 more
openaire   +2 more sources

HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo

Retrovirology, 2019
Background Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Michael P. Martinez, Xiaogang Cheng, Ancy Joseph, Jacob Al-Saleem, Amanda R. Panfil, Marilly Palettas, Wessel P. Dirksen, Lee Ratner, Patrick L. Green   +8 more
doaj   +1 more source

HLA-B*35 as a new marker for susceptibility to human T-cell lymphotropic virus type 1 (HTLV-1) Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in patients living in Argentina

Retrovirology, 2020
Background Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV associated myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) and Adult T cell leukemia/lymphoma (ATLL), in around 2–5% of the infected individuals.
Paula Benencio, Sindy A. Fraile Gonzalez, Nicolás Ducasa, Kimberly Page, Carolina A. Berini, Mirna M. Biglione   +5 more
doaj   +1 more source

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

Journal of Neuro-Oncology, 2013
Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell.
J. Akers, D. Gonda, R. Kim, B. Carter, Clark C. Chen   +4 more
semanticscholar   +1 more source

Retrovirus-like Gag protein Arc1 binds RNA and traffics across synaptic boutons

Cell, 2018
Summary Arc/Arg3.1 is required for synaptic plasticity and cognition and mutations in this gene are linked to autism and schizophrenia. Arc bears a domain resembling retroviral/retrotransposon Gag-like proteins, which multimerize into a capsid that ...
J. Ashley, Benjamin Cordy, Diandra Lucia, L. Fradkin, V. Budnik, Travis C. Thomson   +5 more
semanticscholar   +1 more source

Betaretrovirus infections in dromedary camels in Saudi Arabia

Veterinary Medicine and Science, 2022
Background Retroviral infections have been reported in many species of animals, especially cattle, sheep and goats. However, there are no available reports about retrovirus infection in dromedary camels. Several dromedary camels showed visible tumor‐like
Maged Gomaa Hemida, Abdelmohsen A. Alnaeem   +1 more
doaj   +1 more source

HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models

Frontiers in Immunology, 2022
Human T-cell leukemia virus type 1 (HTLV-1) is the causative infectious agent of adult T-cell leukemia/lymphoma (ATL) and chronic neurological disease.
Victoria Maksimova, Susan Smith, Jaideep Seth, Cameron Phelps, Stefan Niewiesk, Yorifumi Satou, Patrick L. Green, Patrick L. Green, Amanda R. Panfil, Amanda R. Panfil   +9 more
doaj   +1 more source

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

Proceedings of the National Academy of Sciences of the United States of America, 1982
A retrovirus (ATLV) was unequivocally demonstrated in human adult T-cell leukemia (ATL) cell lines by density (1.152-1.155 g/cm3) in a sucrose gradient, reverse transcriptase activity insensitive to actinomycin D, RNA labeled with [3H]uridine, and ...
M. Yoshida, I. Miyoshi, Y. Hinuma
semanticscholar   +1 more source