Results 51 to 60 of about 120,627 (303)

Evidence of extensive non-allelic gene conversion among LTR elements in the human genome [PDF]

, 2016
Long Terminal Repeats (LTRs) are nearly identical DNA sequences found at either end of Human Endogenous Retroviruses (HERVs). The high sequence similarity that exists among different LTRs suggests they could be substrate of ectopic gene conversion events.
CRUCIANI, Fulvio, D'ATANASIO, EUGENIA, Fantini, Gloria, Sellitto, Daniele, TROMBETTA, BENIAMINO   +4 more
core   +1 more source

Endogenous retroviruses [PDF]

Current Biology, 2015
Endogenous retroviruses are integral features of vertebrate genomes. Here, Hayward and Katzourakis offer a glimpse into the fascinating world of these mysterious partners in our evolution.
Hayward, Alexander, Katzourakis, Aris
openaire   +2 more sources

Multiple groups of endogenous epsilon-like retroviruses conserved across primates [PDF]

, 2014
Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often described as
Altschul, Arnaud, Arnold, Baillie, Bannert, Basta, Betancur-R, Brown, Chen, Coffin, Creevey, Gifford, Guindon, Herniou, Jensen-Seaman, Jurka, K. Brown, Katoh, Katzourakis, Keightley, Kent, Krupp, Lepa, Masahito, McCarthy, Meredith, Nellaker, Oja, Paul, Perelman, Polavarapu, R. D. Emes, R. E. Tarlinton, Rice, Rovnak, Shen, Sinzelle, Slater, Smith, Statistics and Information Service, Fisheries and Aquaculture Department, Stocking, Tristem, VanDeValk   +42 more
core   +2 more sources

Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]

, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli, Daniele Saraulli, Felice Tirone, Giorgio D’Andrea, Laura Micheli, Manuela Ceccarelli, Marco Costanzi, Roberta Gioia, Stefano Farioli-Vecchioli, Vincenzo Cestari   +9 more
core   +2 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Steve Oroszlan: A Personal Perspective

Viruses, 2021
My memories of Steve go back over 50 years. While precise dates are no longer in my memory bank, circumstances and emotions remain alive and easy to recall.
Raymond Gilden
doaj   +1 more source

Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA [PDF]

, 2017
From the 13th to 16th February 2017, researchers from around the world convened for the 24th annual Conference on Retroviruses and Opportunistic Infections (CROI) at the Washington State Convention Center in Seattle, Washington.
Bhagani, Sanjay, Colby, Donn J, Crowell, Trevor A, Gathogo, Esther N, Hill, Andrew, Hsu, Denise, Kinloch, Sabine, Lyall, Hermione, Malatinková, Eva, Polyak, Christina, Psomas, Christina, Trypsteen, Wim, Vandekerckhove, Linos   +12 more
core   +2 more sources

Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]

, 2017
BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi, Bittmann, Claire Crossan, Clemenceau, Clemenceau, Cooper, Denner, Denner, Denner, Dieckhoff, Fishman, Gazda, Guo, Irgang, Kimsa, Korbutt, Linda Scobie, Matsumoto, Mazurek, Moon, Morozov, Mourad, Mueller, Nizar I. Mourad, Patience, Pierre Gianello, Pizzato, Schuurman, Scobie, Spizzo, Sypniewski, Tacke, Tucker, Victoria Cruikshank, Wynyard, Wynyard, Zhang   +36 more
core   +1 more source