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Terpenoids: Emerging Natural Modulators for Reversing ABC Transporter-Mediated Multidrug Resistance in Cancer Chemotherapy [PDF]

open access: yesPharmaceuticals
Multidrug resistance (MDR) is a central cause of chemotherapy failure and tumor recurrence and metastasis, and its mechanism involves enhanced drug efflux, target mutation, upregulation of DNA repair and remodeling of the tumor microenvironment.
Lanfei Ma   +8 more
doaj   +2 more sources

Observation of time-reversal symmetry breaking in the band structure of altermagnetic RuO2 [PDF]

open access: yesScience Advances, 2023
Altermagnets are an emerging elementary class of collinear magnets. Unlike ferromagnets, their distinct crystal symmetries inhibit magnetization while, unlike antiferromagnets, they promote strong spin polarization in the band structure.
O. Fedchenko   +23 more
semanticscholar   +1 more source

Time-reversal symmetry-breaking charge order in a kagome superconductor [PDF]

open access: yesNature, 2021
The kagome lattice1, which is the most prominent structural motif in quantum physics, benefits from inherent non-trivial geometry so that it can host diverse quantum phases, ranging from spin-liquid phases, to topological matter, to intertwined orders2–8
C. Mielke   +19 more
semanticscholar   +1 more source

The modes of magnetic field generation in a low-mode model of αΩ-dynamo with α-generator varying intensity regulated by a function with an alternating kernel [PDF]

open access: yesEPJ Web of Conferences, 2021
The low-mode model αΩ-dynamo is used in this paper to simulate the modes of magnetic field generation with insignificant changes in the velocity field of a viscous fluid.
Sheremetyeva Olga V., Godomskaya Anna N.
doaj   +1 more source

Diabetes Remission: Myth or Reality?

open access: yesIndian Journal of Medical Specialities, 2023
The rising prevalence of diabetes mellitus (DM) increases the burden of morbidity and mortality worldwide. DM is recognized as an independent risk factor of cardiovascular mortality.
Ashok Kumar   +2 more
doaj   +1 more source

Median clouds and a fast transposition median solver [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2009
The median problem seeks a permutation whose total distance to a given set of permutations (the base set) is minimal. This is an important problem in comparative genomics and has been studied for several distance measures such as reversals.
Niklas Eriksen
doaj   +1 more source

Crystal time-reversal symmetry breaking and spontaneous Hall effect in collinear antiferromagnets [PDF]

open access: yesScience Advances, 2019
Identification of a previously overlooked spontaneous Hall effect mechanism creates opportunities in low-dissipation spintronics. Electrons, commonly moving along the applied electric field, acquire in certain magnets a dissipationless transverse ...
L. vSmejkal   +3 more
semanticscholar   +1 more source

Effect of Indian Polyvalent Antivenom in the Prevention and Reversal of Local Myotoxicity Induced by Common Cobra (Naja naja) Venom from Sri Lanka In Vitro

open access: yesToxins, 2021
Bites by many Asiatic and African cobras (Genus: Naja) cause severe local dermonecrosis and myonecrosis, resulting in permanent disabilities. We studied the time scale in which two Indian polyvalent antivenoms, VINS and Bharat, remain capable of ...
Umesha Madhushani   +4 more
doaj   +1 more source

Charge reversal nano-systems for tumor therapy

open access: yesJournal of Nanobiotechnology, 2022
Surface charge of biological and medical nanocarriers has been demonstrated to play an important role in cellular uptake. Owing to the unique physicochemical properties, charge-reversal delivery strategy has rapidly developed as a promising approach for ...
Peng Zhang   +3 more
semanticscholar   +1 more source

Different Risk Factors Associated with Persistence or Regression of Squamous Intraepithelial Lesions of Cervix under Rural Conditions in India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: In many Human Papilloma Virus (HPV) negative women, the Squamous Intraepithelial Lesions (SIL) of cervix often show persistence or progression of the lesion on followup which shows involvement of other risk factors of carcinoma cervix ...
Jata Shanker Misra   +2 more
doaj   +1 more source

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