Results 61 to 70 of about 1,390,032 (400)

Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter

open access: yesFrontiers in Oncology, 2020
The efficacy of anti-cancer drugs in patients can be attenuated by the development of multi-drug resistance (MDR) due to ATP-binding cassette (ABC) transporters overexpression.
Hai-Ling Gao   +12 more
doaj   +1 more source

The Importance of Perceived Procedural Justice Among Defendants With a Non-Western Background Involved in Dutch Criminal Cases

open access: yesFrontiers in Psychology, 2021
This study aims to put perceived procedural justice to a critical test in the context of Dutch criminal court hearings. To that end, we surveyed 198 criminal defendants to examine whether their perceptions of procedural fairness were significantly ...
Lisa F. M. Ansems   +3 more
doaj   +1 more source

A thalamocortical circuit for updating action-outcome associations

open access: yeseLife, 2019
The ability to flexibly use knowledge is one cardinal feature of goal-directed behaviors. We recently showed that thalamocortical and corticothalamic pathways connecting the medial prefrontal cortex and the mediodorsal thalamus (MD) contribute to ...
Virginie Fresno   +4 more
doaj   +1 more source

Median clouds and a fast transposition median solver [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2009
The median problem seeks a permutation whose total distance to a given set of permutations (the base set) is minimal. This is an important problem in comparative genomics and has been studied for several distance measures such as reversals.
Niklas Eriksen
doaj   +1 more source

Magnetic Reversal on Vicinal Surfaces

open access: yes, 1998
We present a theoretical study of in-plane magnetization reversal for vicinal ultrathin films using a one-dimensional micromagnetic model with nearest-neighbor exchange, four-fold anisotropy at all sites, and two-fold anisotropy at step edges. A detailed
A. Berger   +41 more
core   +1 more source

Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation. [PDF]

open access: yes, 2013
Achieving efficient β-cell regeneration is a major goal of diabetes research. Previously, we found that a combination of β-cell ablation and pancreatic duct ligation led to β-cell regeneration by direct conversion from α-cells.
Hao, Ergeng   +2 more
core   +1 more source

Reversible Cardiomyopathies

open access: yesClinical Medicine Insights: Cardiology, 2015
Cardiomyopathies (CMs) have many etiological factors that can result in severe structural and functional dysregulation. Fortunately, there are several potentially reversible CMs that are known to improve when the root etiological factor is addressed. In this article, we discuss several of these reversible CMs, including tachycardia-induced, peripartum,
Harsh Patel   +4 more
openaire   +4 more sources

Unconventional superconductivity with a sign reversal in the order parameter of LaFeAsO1-xFx. [PDF]

open access: yesPhysical Review Letters, 2008
We argue that the newly discovered superconductivity in a nearly magnetic, Fe-based layered compound is unconventional and mediated by antiferromagnetic spin fluctuations, though different from the usual superexchange and specific to this compound.
I. Mazin   +3 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Re-expression of SynGAP protein in adulthood improves translatable measures of brain function and behavior

open access: yeseLife, 2019
It remains unclear to what extent neurodevelopmental disorder (NDD) risk genes retain functions into adulthood and how they may influence disease phenotypes. SYNGAP1 haploinsufficiency causes a severe NDD defined by autistic traits, cognitive impairment,
Thomas K Creson   +10 more
doaj   +1 more source

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