Results 51 to 60 of about 23,572,323 (347)

Touchscreen-based Visual Discrimination and Reversal Tasks for Mice to Test Cognitive Flexibility

open access: yesBio-Protocol, 2017
Reversal learning can be used to examine deficits in cognitive flexibility, which have been linked to a number of neuropsychiatric disorders including schizophrenia and addiction.
Karly Turner   +2 more
doaj   +1 more source

Effects of mechano-electric feedback on scroll wave stability in human ventricular fibrillation. [PDF]

open access: yesPLoS ONE, 2013
Recruitment of stretch-activated channels, one of the mechanisms of mechano-electric feedback, has been shown to influence the stability of scroll waves, the waves that underlie reentrant arrhythmias. However, a comprehensive study to examine the effects
Yuxuan Hu   +4 more
doaj   +1 more source

CRF-receptor1 modulation of the dopamine projection to prelimbic cortex facilitates cognitive flexibility after acute and chronic stress

open access: yesNeurobiology of Stress, 2022
Stress reduces cognitive flexibility and dopamine D1 receptor-related activity in the prelimbic cortex (PL), effects hypothesized to depend on reduced corticotropic releasing factor receptor type 1 (CRFr1) regulation of dopamine neurons in the ventral ...
David Mor   +4 more
doaj   +1 more source

Antibody‐Based Ticagrelor Reversal Agent in Healthy Volunteers

open access: yesNew England Journal of Medicine, 2019
Background Ticagrelor is an oral P2Y12 inhibitor that is used with aspirin to reduce the risk of ischemic events among patients with acute coronary syndromes or previous myocardial infarction.
Deepak L. Bhatt   +8 more
semanticscholar   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Direct test of time reversal symmetry in the entangled neutral kaon system at a phi-factory [PDF]

open access: yes, 2012
We present a novel method to perform a direct T (time reversal) symmetry test in the neutral kaon system, independent of any CP and/or CPT symmetry tests.
J. Bernabéu   +2 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Delay in loop ileostomy reversal surgery does not impact upon post-operative clinical outcomes. Complications are associated with an increased loss of microflora in the defunctioned intestine

open access: yesGut Microbes, 2023
Loop ileostomy is a common surgical procedure to allow downstream tissue healing, with the aim of re-joining the bowel approximately 12 months later. The reversal procedure is associated with a substantial morbidity up to 40%.
Emma L. Beamish   +9 more
doaj   +1 more source

Test of the universality of naive-time-reversal-odd fragmentation functions. [PDF]

open access: yesPhysical Review Letters, 2010
We investigate the "spontaneous" hyperon transverse polarization in e+ e- annihilation and semi-inclusive deep inelastic scattering processes as a test of the universality of the naive-time-reversal-odd transverse momentum dependent fragmentation ...
D. Boer, Z. Kang, W. Vogelsang, F. Yuan
semanticscholar   +1 more source

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