Results 61 to 70 of about 23,572,323 (347)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Test Submission

open access: yes, 2021
This is a sample submission generated by Vireo to test the repository deposit features.Test ...
Submitter, Test
core  

Effectiveness analysis of impact location algorithm for composite reinforced structures

open access: yesHangkong gongcheng jinzhan, 2023
With the large-scale application of composite materials in aircraft structures, the threat of visually invisible damage such as internal delamination of composite materials caused by impact from foreign objects is increasing,therefore, impact event ...
ZHANG Yang, YANG Yu, QI Ge, ZHANG Sheng
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Test Submission

open access: yes
This is a sample submission generated by Vireo to test the repository deposit ...
Submitter, Test
core   +4 more sources

A Survey of TEPIX Efficiency [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2006
This paper is aimed to respond to a general question about the capacity and potency of Tehran Stock Exchange Price Index (TEPIX) - an all-share Index- indicating future movement of the market and economy as a leading indicator.
Mohammad Reza Sarebanha   +2 more
doaj  

Subduction flux modulates the geomagnetic polarity reversal rate

open access: yesTectonophysics, 2018
Ascertaining the cause of variations in the frequency of geomagnetic polarity reversals through the Phanerozoic has remained a primary research question straddling paleomagnetism and geodynamics for decades.
M. Hounslow, M. Domeier, A. Biggin
semanticscholar   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analysis of the influencing factors on serum reversal in HIV-exposed children [PDF]

open access: yesYixue xinzhi zazhi
Objective To study the factors influencing serum reversal in HIV-exposed children.Methods The general information, clinical data, and serum results of 49 cases of HIV-infected pregnant women and their children exposed to HIV were collected from the ...
LI Xiaoling   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy