Results 181 to 190 of about 47,754 (258)

Recurrent wide complex tachycardia: Where is the target for ablation? [PDF]

Indian Pacing Electrophysiol J
Kataoka S, Gerstenfeld EP.
europepmc   +1 more source

Claustrum Involvement in New Onset Refractory Status Epilepticus: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The claustrum sign is a distinctive neuroimaging finding characterized by bilateral T2/FLAIR hyperintensity of the claustrum, one of the most interconnected regions of the human brain. It was first described in new‐onset refractory status epilepticus (NORSE) and febrile infection–related epilepsy syndrome (FIRES).
Margherita Burani, Lorenzo Muccioli, Giada Giovannini, Niccolò Orlandi, Francesca Bisulli, Stefano Meletti   +5 more
wiley   +1 more source

Autograft Polarity on Functional Outcomes Following Experimental Peripheral Nerve Repair Surgery: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Kim HO, Oh YJ, Kim SS, Kim YJ, Choi JW, Lee JM, Yeo SG.   +6 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Biomolecular mechanisms of cardiac amyloidosis and its cardiovascular pathological basis. [PDF]

Front Immunol
Zhang L, Jiao Y, Guo J.
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

A digital twin approach for simultaneous reconstruction of brain anatomy and dynamics from neural data. [PDF]

PLOS Digit Health
Fabbrizzi M, Amato LG, Martinelli L, Carpaneto J, Bartolini E, Calderoni S, Retico A, Vergani AA, Mazzoni A.   +8 more
europepmc   +1 more source

Early reversal of cardiac remodeling in patients with new-onset persistent left bundle branch block after transcatheter aortic valve replacement. [PDF]

J Cardiothorac Surg
Wang S, Tan K, Gao X, Zhang L, Liu C, Huang X, Yan S, Guo J, Xiong F.   +8 more
europepmc   +1 more source