Results 131 to 140 of about 4,446,471 (346)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Reverse engineering of CAD models via clustering and approximate implicitization
, 2020 In applications like computer aided design, geometric models are often represented numerically as polynomial splines or NURBS, even when they originate from primitive geometry. For purposes such as redesign and isogeometric analysis, it is of interest to
Barrowclough, Oliver J. D. +2 more
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Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Reverse engineering of intravascular catheters
Модели, системы, сети в экономике, технике, природе и обществеBackground. The creation of competitive products is the main task of various branches of industrial production. The solution of these problems is possible due to the use of polymer layered composite materials.
E.D. Kartashova, A.Yu. Muyzemnek
doaj +1 more source
Making copies of religious culture relics using reverse engineering [PDF]
, 2020 Bartosz Pieróg +2 more
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
APLIKASI TEKNOLOGI DIGITAL PROTOTYPING PADA REVERSE ENGINEERING PROTESA ATAS LUTUT PADA KLINIK ORPROS`T [PDF]
, 2010 APLIKASI TEKNOLOGI DIGITAL PROTOTYPING PADA REVERSE ENGINEERING PROTESA ATAS LUTUT PADA KLINIK ORPROS`T - Pengembangan Produk, Analisa Kebutuhan Pasar, Reverse Engineering ...
GARJITO, GELAR +2 more
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