Results 141 to 150 of about 4,446,471 (346)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Reverse Engineering and Cognition Panglossian Memories?
Daniel C. Dennett has dedicated a great part of his work to the conception of an application of reverse engineering and adaptationism in order to explain the evolution of the human mind.
Liliana Chaves Castaño +1 more
doaj
A Survey on Application of AI on Reverse Engineering for Software Analysis and Security
Reverse engineering process serves essential functions in software analysis and security auditing and malware detection but requires significant time and effort.
Ashutosh Ghimire +4 more
doaj +1 more source
The Effectiveness Of Bytecode Decompilation [PDF]
High-level bytecodes used by object-oriented managed execution environments make it easy to decompile them. This paper studies the reasons that make bytecode decompilers such efficient and presents basic obfuscation techniques as an efficient protection ...
Robert Enyedi
core
Utilizing the technique of industrial computed tomography (iCT) in reverse engineering field for industrial products [PDF]
Kareem Mustafa
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Reverse Engineering Socialbot Infiltration Strategies in Twitter [PDF]
Data extracted from social networks like Twitter are increasingly being used to build applications and services that mine and summarize public reactions to events, such as traffic monitoring platforms, identification of epidemic outbreaks, and public ...
Adriano Veloso +4 more
core +1 more source
Layout-Only Hardware Trojans: Attack Vectors and a Non-Golden Model Reverse Engineering-Based Counterstrategy [PDF]
Matthias Ludwig +2 more
openalex +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

