Results 181 to 190 of about 5,819,690 (295)

PREE: Heuristic builder for reverse engineering of network protocols in industrial control systems. [PDF]

Forensic Sci Int Digit Investig, 2023
Qasim SA, Jo W, Ahmed I.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A Quantitative Method for 3D Scan Quality Assessment Under Different Surface Conditions for Reverse Engineering of Shipyard Components. [PDF]

Sensors (Basel)
Freni F, Panfiglio S, Abdalla E, Cannuli A, Di Bella G, Montanini R.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Reverse engineering molecules from fingerprints through deterministic enumeration and generative models. [PDF]

J Cheminform
Meyer P, Duigou T, Gricourt G, Faulon JL.   +3 more
europepmc   +1 more source

Reverse Engineering and 3D Printing of Medical Devices for Drug Delivery and Drug-Embedded Anatomic Implants. [PDF]

Polymers (Basel), 2023
Elumalai A, Nayak Y, Ganapathy AK, Chen D, Tappa K, Jammalamadaka U, Bishop G, Ballard DH.   +7 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluation of the Dimensional Accuracy of 3D-Printed Aligners: An In Vitro Study Using Reverse Engineering Analysis. [PDF]

J Funct Biomater
Avolese S, Sanna F, Parrini S, Chiarello G, Lava D, Sedran A, Deregibus A, Scotti N.   +7 more
europepmc   +1 more source

CDiP technology for reverse engineering of sporadic Alzheimer's disease. [PDF]

J Hum Genet, 2023
Kondo T, Yada Y, Ikeuchi T, Inoue H.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source