Results 201 to 210 of about 4,446,471 (346)

Automatic Train Control (ATC) System Development through Application of Reverse and Re-Systems Engineering Process [PDF]

, 2003
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openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Decoding the Solution for Man-at-the-End Attacks and Reverse Engineering on IoMT Devices: An Experimental Review of Techniques and Defences. [PDF]

J Multidiscip Healthc
T AH, Sriraman H.
europepmc   +1 more source

Reverse Engineering of Digital Measures: Inviting Patients to the Conversation. [PDF]

Digit Biomark, 2023
Clay I, Peerenboom N, Connors DE, Bourke S, Keogh A, Wac K, Gur-Arie T, Baker J, Bull C, Cereatti A, Cormack F, Eggenspieler D, Foschini L, Ganea R, Groenen PMA, Gusset N, Izmailova E, Kanzler CM, Leyens L, Lyden K, Mueller A, Nam J, Ng WF, Nobbs D, Orfaniotou F, Perumal TM, Piwko W, Ries A, Scotland A, Taptiklis N, Torous J, Vereijken B, Xu S, Baltzer L, Vetter T, Goldhahn J, Hoffmann SC.   +36 more
europepmc   +1 more source

A selection of distinguished papers from the 19th Working Conference on Reverse Engineering 2012 [PDF]

, 2014
Rocco Oliveto, Denys Poshyvanyk
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists. [PDF]

Comput Struct Biotechnol J, 2023
Shirt-Ediss B, Connolly J, Elezgaray J, Torelli E, Navarro SA, Bacardit J, Krasnogor N.   +6 more
europepmc   +1 more source

Reverse Engineering High-Level Resistance to Bt Cry1ac Toxin in Plutella Xylostella Reveals a Hormonal Regulatory Feedback Pathway

Dan Sun, Mingyun Wang, Le Guo, Xuping Shentu, Xiaoping Yu, Neil Crickmore, Xuguo Zhou, Youjun Zhang, Zhaojiang Guo   +8 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Design of orthogonal and portable RNA devices for post-transcriptional regulation by reverse engineering type I toxin-antitoxin systems. [PDF]

Nucleic Acids Res
Yin G, Zhang L, Zhou D, Zhou S, Xu R, Du G, Chen J, Kang Z.   +7 more
europepmc   +1 more source