Results 131 to 140 of about 1,799,385 (351)

tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes

, 2006
Infection of non-dividing cells is a biological property of HIV-1 crucial for virus transmission and AIDS pathogenesis. This property depends on nuclear import of the intracellular reverse transcription and pre-integration complexes (RTCs/PICs).
Zaitseva Lyubov, Fassati Ariberto, Myers Richard, Myers, R, Lyubov Zaitseva, Ariberto Fassati, Fassati, A, Richard Myers, Zaitseva, L   +8 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Human telomerase reverse transcriptase expression in ovarian tumors

Indian Journal of Pathology and Microbiology, 2012
Background : Ovarian cancer is the 6 th most common cancer among women. In ovarian tumors, the borderline category is not well defined due to the difficulty in assessing stromal invasion. The World Health Organization (WHO) defined it as tumor that lacks
Awadh Ali Makhashen Maraei, Ahmad Zailani Hatta, Mohd Sidik Shiran, Geok Chin Tan   +3 more
doaj   +1 more source

Primers used for reverse transcriptase PCR.

, 2019
Primers used for reverse transcriptase PCR.
Michael Linnebacher (180341), Falko Lange (108694), Timo Kirschstein (3737260), Katrin Porath (5572574), Christina Susanne Mullins (443088), Carina Bergner (6294128), Bernd Joachim Krause (818236), Rüdiger Köhling (501919), Konrad Weßlau (6294122), Julia Hörnschemeyer (6294125)   +9 more
core   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

Advanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang, Yifeng Wei, Xumei Liu, Dazhi Liu, Zhenyu Liu, Yang Tong, Jinyu Yin, Ankanahalli N. Nanjaraj Urs, Meining Xing, Mark A. Harrison, Chuyuan Zhang, Sheng Yang, Yunzi Luo, Ee Lui Ang, Huimin Zhao, Yan Zhang   +15 more
wiley   +1 more source

Primers used for Quantitative reverse-transcriptase PCR.

, 2017
Primers used for Quantitative reverse-transcriptase PCR.
Payal Agarwal (3625829), Maninder Sandey (3625832), Abdul Mohin Sajib (3625835), Bruce F. Smith (3625823), Elizabeth A. Gammon (3625826)   +4 more
core   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Oligonucleotide primers used for reverse transcriptase PCR.

, 2013
Oligonucleotide primers used for reverse transcriptase PCR.
Julie Naughton (304065), Marguerite Clyne (304068), Brendan Dolan (304063), Nicole Tegtmeyer (304066), Felicity E. B. May (304067)   +4 more
core   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

A Review of Electroanalytical Techniques for Determination of Anti-HIV Drugs

International Journal of Electrochemistry, 2011
Until now after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of ...
Burçin Bozal, Bengi Uslu, Sibel A. Özkan   +2 more
doaj   +1 more source