Results 131 to 140 of about 965,759 (306)

Unusual Reverse Transcriptases [PDF]

Journal of Biological Chemistry, 1995
openaire   +2 more sources

Primers used in Reverse-transcriptase Quantitative PCR (RT-qPCR) analysis.

, 2013
Primers used in Reverse-transcriptase Quantitative PCR (RT-qPCR) analysis.
Juthatip Prommoon (344745), Amornpan Klanchui (107611), Nitsara Karoonuthaisiri (107618), Umaporn Uawisetwathana (107615), Rungnapa Leelatanawit (107607), Sirawut Klinbunga (298544)   +5 more
core   +1 more source

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

Advanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian, Juze Yang, Jiayi Ren, Xiaowei Mao, Jia Li, Tengfei Sun, Liangliang Dong, Enguo Chen, Yan Lu, Pengyuan Liu   +9 more
wiley   +1 more source

Reverse-transcriptase–PCR primer sequences and used annealing temperatures.

, 2012
Reverse-transcriptase–PCR primer sequences and used annealing temperatures.
Kati Juuti-Uusitalo (187668), Tuomas Ryhänen (187684), Susanna Narkilahti (187687), Riitta Suuronen (187688), Hanna Vaajasaari (187679), Kai Kaarniranta (187693), Heli Skottman (61007), Eliisa Mannermaa (187691)   +7 more
core   +1 more source

Molecular Signatures of HIV‐Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV

Advanced Science, EarlyView.
HIV preferentially infects microglia, activating IL‐17A‐driven IFN‐γ/STAT1, CEBPB, and NF‐κB signaling that converges with cGAS‐STING and Notch–NEURL1 pathways, promoting neuroinflammation, mitochondrial dysfunction, and synaptic impairment. cART suppresses viral replication, attenuates inflammatory signaling, and at least partially restores ...
Karthick Chennakesavan, Malaroviyam Samikkannu, Shreyan Gupta, Olasunkanmi Israel Tayo, Arpan Acharya, James J. Cai, Siddappa N. Byrareddy, Thangavel Samikkannu   +7 more
wiley   +1 more source

Primer sets for reverse transcriptase-polymerase chain reaction analysis.

, 2013
Primer sets for reverse transcriptase-polymerase chain reaction analysis.
Wen-Qi Lai (350121), Li Ren Kong (350119), Fera Y. Goh (350115), Chang Cheng (350112), W. Eugene Ho (350113), Bernard P. Leung (350122), Shou Ping Guan (350117), W. S. Fred Wong (350123)   +7 more
core   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Distribution of reverse transcriptase resistance-associated mutations among 1,798 antiretroviral-naive HIV-infected patients.

, 2013
Abbreviations: NRTI; nucleoside reverse transcriptase inhibitor, NNRTI; non-nucleoside reverse transcriptase inhibitor.
Awachana Jiamsakul (427727), Adeeba Kamarulzaman (307011), Rossana Ditangco (361612), Christopher Lee (11627), Annette H. Sohn (427730), Pacharee Kantipong (311441), Patrick C. K. Li (427728), Winai Ratanasuwan (427729), Sasisopin Kiertiburanakul (427725), Sunee Sirivichayakul (7870), Somnuek Sungkanuparph (427731), Romanee Chaiwarith (427726)   +11 more
core   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

Advanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan, Lin‐Fei Jiao, Pei‐Pei Liu, Chun‐Hui Duan, Xiao Li, Zi‐Han Zhang, Yue‐Qi Zhang, Xin‐Li Ouyang, Hong‐Zhen Du, Sha Liu, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu   +12 more
wiley   +1 more source

Combined analysis of Two-Year Follow-up from two open-label randomized trials comparing efficacy of three nucleoside reverse transcriptase inhibitor backbones for previously untreated HIV-1 nfection: OzCombo 1 and 2 [PDF]

, 2003
Purpose: To compare inhibition of HIV replication, improvements in CD4+ T-cell counts, metabolic parameters, and body shape changes after 2 years of assigned therapy in OzCombo patients.
Cooper, D.A., Todhunter, L., Sowden, D., Hoy, J.N., Papanaoum, K., Quin, J., Genn, W., Amin, J., Mulholland, J., Bryant, M., Shaw, D.V., Ferguson, W., Baker, D., Moore, A., Scull, N., James, R., French, M.A., Street, A., Packham, D., Foreman, E., Doong, N.C., Rawlinsen, M., McCormack, C., Norrito, L., Dwyer, D., Quan, D., Roney, J., Waddell, R., French, M.R., Carr, A., De Graaf, B., Garsia, R., Law, M., Beveridge, A., Kotsiou, G., Fordham, M., Emery, S., Rebic, D., Mallal, S.   +38 more
core