Results 1 to 10 of about 203,406 (266)

Directed evolution of enzymes at the crossroads of tradition and innovation. [PDF]

FEBS Open Bio
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Tomkova M, Mirossay A, Sedlak E.
europepmc   +2 more sources

Ubiquitin-Dependent Regulation of Influenza A Virus Polymerase and vRNP Function: Mechanisms and Therapeutic Opportunities. [PDF]

Microorganisms
Cao R, Guo F, Huang T, Zhang Y, Chen Y, Yuan J, Fu T, Wang Z, Liu D.   +8 more
europepmc   +1 more source

RNA-directed DNA-polymerase activity in Greene hamster melanoma.

The Yale journal of biology and medicine, 1974
T W, Reid, T L, Darling, P, Russell, D M, Albert   +3 more
openaire   +1 more source

Evolution of Epigenetic Regulation in Plant Reproduction. [PDF]

Epigenomes
Brukhin V.
europepmc   +1 more source

Structural and single-molecule insights into the core human mitochondrial DNA replisome. [PDF]

Biochem J
Plaza-G A I, Miguez-Amil S, Hayes AM, Ciesielski GL, Fernandez-Leiro R, Ibarra B.   +5 more
europepmc   +1 more source

The Single-Stranded DNA Platform: A Potential Broad-Spectrum Vector for Editing Genes in Prokaryotes: ssDNA May Break Through the Difficulties of Genetic Manipulation on Non-Model Bacteria. [PDF]

Bioessays
Wang H, Wang Y, Chang D, Fang J, Zheng Z, Wang X, Yang H, Liu Z.   +7 more
europepmc   +1 more source

ERCC6 at the Transcription-Replication Interface: Integration of Transcription-Coupled Repair with Replication Stress Responses. [PDF]

Int J Mol Sci
Zambrano E, Morales F, Bernal YA, Marcelain K.   +3 more
europepmc   +1 more source

Alpha-like subunits of multisubunit RNA polymerases: insights into structure, function, and disease. [PDF]

RNA Biol
Onuoha OC, Belkevich AE, Palumbo RJ, Knutson BA.   +3 more
europepmc   +1 more source

HUSH, NEXT PROMPT: Epigenetics and the Nuclear RNA Exosome in Human Aging and Disease. [PDF]

Cells
Newman AG, Singh PB.
europepmc   +1 more source

Alternative nucleic acid structures in microbial biology: regulatory functions and antimicrobial opportunities. [PDF]

Front Cell Infect Microbiol
Yousuf S, M M, Bhat S.
europepmc   +1 more source