Dynamic regulation of ARGONAUTE4 within multiple nuclear bodies in Arabidopsis thaliana. [PDF]
PLoS Genetics, 2008 DNA methylation directed by 24-nucleotide small RNAs involves the small RNA-binding protein ARGONAUTE4 (AGO4), and it was previously shown that AGO4 localizes to nucleolus-adjacent Cajal bodies, sites of snRNP complex maturation. Here we demonstrate that
Carey F Li +5 more
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The Rise and Fall of Billionaire siRNAs during Reproductive Development in Rice
Plants, 2022 RNA polymerase IV-dependent siRNAs, usually 24 nt in length, function in the RNA-directed DNA methylation that is responsible for de novo methylation in plants.
Lili Wang +3 more
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New link between the RNA polymerase II-CTD and replication stress
Molecular & Cellular Oncology, 2021 Conflicts between transcription and replication are a major source of replication stress. Our recent findings show that proper dephosphorylation of Serine 5 in the carboxy-terminal domain (CTD) of DNA-directed RNA polymerase II subunit RPB1 is needed to ...
Helga B. Landsverk +3 more
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Primer recognition by avian myeloblastosis virus RNA-directed DNA polymerase [PDF]
Journal of Virology, 1977 Tryptophanyl-tRNA was specifically labeled at the 3' end with [3H]tryptophan and cleaved in half with RNase under denaturing conditions, and the 3' half was shown to hybridize exclusively at the 5' end of avian myeloblastosis virus RNA. The RNA-dependent DNA polymerase of avian myeloblastosis virus is capable of efficiently binding the 3' half of the ...
R D, Brown, R W, Armentrout
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Production and processing of siRNA precursor transcripts from the highly repetitive maize genome. [PDF]
PLoS Genetics, 2009 Mutations affecting the maintenance of heritable epigenetic states in maize identify multiple RNA-directed DNA methylation (RdDM) factors including RMR1, a novel member of a plant-specific clade of Snf2-related proteins.
Christopher J Hale +3 more
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Endogenous RNA-Directed DNA Polymerase Activity in Uninfected Chicken Embryos [PDF]
Proceedings of the National Academy of Sciences, 1972 Early chicken embryos that are either positive or negative for group-specific antigens of avian leukosis viruses contained endogenous RNA-directed DNA polymerase activity. This endogenous DNA polymerase activity was not increased after mixture of soluble DNA polymerases isolated from chicken embryos with disrupted chicken embryo cells.
C Y, Kang, H M, Temin
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DNA polymerase of reticuloendotheliosis virus: Inability to detect endogenous RNA-directed DNA synthesis [PDF]
Virology, 1975 Abstract Purified preparations of reticuloendotheliosis virus (REV) appear to lack the endogenous RNase-sensitive DNA polymerase activity present in most, if not all, avian RNA tumor viruses. Although no endogenous RNA-directed DNA polymerase could be detected in REV, we have been able to demonstrate the presence of a virion-associated DNA polymerase
Kieras, Rita M., Faras, Anthony J.
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The ability to form homodimers is essential for RDM1 to function in RNA-directed DNA methylation. [PDF]
PLoS ONE, 2014 RDM1 (RNA-DIRECTED DNA METHYLATION1) is a small plant-specific protein required for RNA-directed DNA methylation (RdDM). RDM1 interacts with RNA polymerase II (Pol II), ARGONAUTE4 (AGO4), and the de novo DNA methyltransferase DOMAINS REARRANGED ...
Taku Sasaki +4 more
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Arabidopsis C-terminal domain phosphatase-like 1 functions in miRNA accumulation and DNA methylation. [PDF]
PLoS ONE, 2013 Arabidopsis CTD-PHOSPHATASE-LIKE 1 (CPL1) is a protein phosphatase that can dephosphorylate RNA polymerase II C-terminal domain (CTD). Unlike typical CTD-phosphatases, CPL1 contains a double-stranded (ds) RNA-binding motif (dsRBM) and has been implicated
In Sil Jeong +7 more
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Inhibition of RNA-directed DNA polymerase by aurintricarboxylic acid.
Nucleic Acids Research, 1976 Commercial-grade aurintricarboxylic acid (ATA) inhibits poly(A), poly(C) and viral RNA-directed DNA synthesis by detergent-disrupted virions of Moloney murine leukemia virus. Paper chromatography of crude ATA yields two active components, which appear to behave identically, and at least two inactive components.
J F, Givens, K F, Manly
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