Results 31 to 40 of about 203,406 (266)

Genomic analysis of Poxviridae and exploring qualified gene sequences for phylogenetics

Computational and Structural Biotechnology Journal, 2021
The members of the Poxviridae family are globally distributed all over the world and can cause infectious diseases. Although genome sequences are publicly available for representative isolates of all genera, studies on the criteria for genome-based ...
Zehui Yu, Wenjie Zhang, Huancheng Fu, Xiaoxia Zou, Mingde Zhao, Sicheng Liang, Congwei Gu, Qian Yang, Manli He, Qihai Xiao, Wudian Xiao, Lvqin He, Muhan Lü   +12 more
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Morphological and Molecular Characterization of Pseudocercospora chionanthi-retusi Causing Leaf Spot on Chionanthus retusus in Korea [PDF]

Research in Plant Disease, 2022
Leaves of Chionanthus retusus were found to be damaged by leaf spot disease associated with a fungus in Iksan, Korea. Leaf spots were angular to irregular, vein-limited, scattered, 1–8 mm diameter, brownish-gray to dark brown when dry, with heavy ...
In-Young Choi, Lamiya Abasova, Joon-Ho Choi, Hyeon-Dong Shin   +3 more
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Characterization of an RNA-directed DNA polymerase found in association with murine intracytoplasmic A-particles [PDF]

Journal of Virology, 1977
An RNA-directed DNA polymerase was found to be associated with intracytoplasmic A-particles from DBA/2 mouse leukemia cells. The enzyme activity was detected after disrupting the purified particles with 2 M NaCl-20 mM dithiothreitol. The presence of a divalent cation and all four deoxyribonucleoside triphosphates was essential for this enzyme activity.
Kohno, M, Tanaka, H
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Effect of UV Light on RNA-Directed DNA Polymerase Activity of Murine Oncornaviruses [PDF]

Journal of Virology, 1975
The UV inactivation of RNA-directed DNA polymerase activity of Rauscher leukemia virus was shown to be due to damage to the protein. The UV dose resulting in 37% survival of viral polymerase activity at 254 nm was 2.4 × 10 4 to 3.1 × 10 4 ergs/mm 2 .
G G, Lovinger, H P, Ling, R V, Gilden, M, Hatanaka   +3 more
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Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase [PDF]

Journal of Virology, 1978
The avian retrovirus RNA-directed DNA polymerase contains an activity that is capable of removing hydrogen bonds from duplex nucleic acid molecules. This "unwinding-like" activity appears to be specific in its action, affecting RNA.DNA and DNA.DNA duplex molecules but not RNA.RNA duplexes.
M S, Collett, J P, Leis, M S, Smith, A J, Faras   +3 more
openaire   +2 more sources

Extent of Transcription of Mouse Sarcoma-Leukemia Virus by RNA-Directed DNA Polymerase [PDF]

Proceedings of the National Academy of Sciences, 1974
The DNA product obtained from the endogenous RNA-directed DNA polymerase (deoxynucleosidetriphosphate:DNA deoxynucleotidyltransferase, EC 2.7.7.7) reaction of the Moloney sarcoma:leukemia viruses produced by the 78 A-1 cell line was analyzed and characterized.
A, Tavitian, R, Hamelin, P, Tchen, B, Olofsson, M, Boiron   +4 more
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Pol IV-Dependent siRNA Production is Reduced in Brassica rapa

Biology, 2013
Plants produce a diverse array of small RNA molecules capable of gene regulation, including Pol IV-dependent short interfering (p4-si)RNAs that trigger transcriptional gene silencing.
Rebecca A. Mosher, Yi Huang, Timmy Kendall   +2 more
doaj   +1 more source

Dielectricity of a molecularly crowded solution accelerates NTP misincorporation during RNA-dependent RNA polymerization by T7 RNA polymerase

Scientific Reports, 2022
In biological systems, the synthesis of nucleic acids, such as DNA and RNA, is catalyzed by enzymes in various aqueous solutions. However, substrate specificity is derived from the chemical properties of the residues, which implies that perturbations of ...
Shuntaro Takahashi, Saki Matsumoto, Pallavi Chilka, Saptarshi Ghosh, Hiromichi Okura, Naoki Sugimoto   +5 more
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Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1 [PDF]

Nature, 2013
DNA methylation is an epigenetic modification that plays critical roles in gene silencing, development, and genome integrity. In Arabidopsis, DNA methylation is established by DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2) and targeted by 24 nt small interfering RNAs (siRNAs) through a pathway termed RNA-directed DNA methylation (RdDM)1.
Julie A. Law, Jiamu Du, Christopher J. Hale, Suhua Feng, Krzysztof Krajewski 0002, Ana Marie S. Palanca, Brian D. Strahl, Dinshaw J. Patel, Steven E. Jacobsen   +8 more
openaire   +3 more sources

Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity

Biology, 2012
HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme
Michael A. Parniak, Stefan G. Sarafianos, Rieko Ishima, Krystal LaBarge, Tatiana Ilina   +4 more
doaj   +1 more source