Effect of UV Light on RNA-Directed DNA Polymerase Activity of Murine Oncornaviruses [PDF]
Journal of Virology, 1975 The UV inactivation of RNA-directed DNA polymerase activity of Rauscher leukemia virus was shown to be due to damage to the protein. The UV dose resulting in 37% survival of viral polymerase activity at 254 nm was 2.4 × 10 4 to 3.1 × 10 4 ergs/mm 2 .
G G, Lovinger +3 more
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Heterochromatic siRNAs and DDM1 independently silence aberrant 5S rDNA transcripts in Arabidopsis. [PDF]
PLoS ONE, 2009 5S ribosomal RNA gene repeats are arranged in heterochromatic arrays (5S rDNA) situated near the centromeres of Arabidopsis chromosomes. The chromatin remodeling factor DDM1 is known to maintain 5S rDNA methylation patterns while silencing transcription ...
Todd Blevins +3 more
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Genomic analysis of Poxviridae and exploring qualified gene sequences for phylogenetics
Computational and Structural Biotechnology Journal, 2021 The members of the Poxviridae family are globally distributed all over the world and can cause infectious diseases. Although genome sequences are publicly available for representative isolates of all genera, studies on the criteria for genome-based ...
Zehui Yu +12 more
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Morphological and Molecular Characterization of Pseudocercospora chionanthi-retusi Causing Leaf Spot on Chionanthus retusus in Korea [PDF]
Research in Plant Disease, 2022 Leaves of Chionanthus retusus were found to be damaged by leaf spot disease associated with a fungus in Iksan, Korea. Leaf spots were angular to irregular, vein-limited, scattered, 1–8 mm diameter, brownish-gray to dark brown when dry, with heavy ...
In-Young Choi +3 more
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RNA-directed DNA polymerase from particles released by normal goose cells [PDF]
Journal of Virology, 1979 Cells from a goose embryo were shown to release particle-associated RNA-directed DNA polymerase and RNase H activities that required the presence of Nonidet P-40 for detection. The particles were not infectious and did not have endogenous DNA synthesis.
Bauer, Georg, Temin, Howard Martin
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Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase [PDF]
Journal of Virology, 1978 The avian retrovirus RNA-directed DNA polymerase contains an activity that is capable of removing hydrogen bonds from duplex nucleic acid molecules. This "unwinding-like" activity appears to be specific in its action, affecting RNA.DNA and DNA.DNA duplex molecules but not RNA.RNA duplexes.
M S, Collett +3 more
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Pol IV-Dependent siRNA Production is Reduced in Brassica rapa
Biology, 2013 Plants produce a diverse array of small RNA molecules capable of gene regulation, including Pol IV-dependent short interfering (p4-si)RNAs that trigger transcriptional gene silencing.
Rebecca A. Mosher +2 more
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Scientific Reports, 2022 In biological systems, the synthesis of nucleic acids, such as DNA and RNA, is catalyzed by enzymes in various aqueous solutions. However, substrate specificity is derived from the chemical properties of the residues, which implies that perturbations of ...
Shuntaro Takahashi +5 more
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Extent of Transcription of Mouse Sarcoma-Leukemia Virus by RNA-Directed DNA Polymerase [PDF]
Proceedings of the National Academy of Sciences, 1974 The DNA product obtained from the endogenous RNA-directed DNA polymerase (deoxynucleosidetriphosphate:DNA deoxynucleotidyltransferase, EC 2.7.7.7) reaction of the Moloney sarcoma:leukemia viruses produced by the 78 A-1 cell line was analyzed and characterized.
A, Tavitian +4 more
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Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity
Biology, 2012 HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme
Michael A. Parniak +4 more
doaj +1 more source