Results 281 to 290 of about 1,758,180 (373)

DNA polymerase Zeta is a robust reverse transcriptase

open access: green
Ryan Mayle   +2 more
openalex   +1 more source

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

open access: yesBiotechnology and Bioengineering, EarlyView.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes   +4 more
wiley   +1 more source

Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2014
J. Wang   +4 more
semanticscholar   +1 more source

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

open access: yesBMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang   +9 more
wiley   +1 more source

Biological evaluation of inhibitors of reverse transcriptase from HIV type-1

open access: diamond, 2015
Hitendra Kumar Lautre   +3 more
openalex   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

open access: yesCancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang   +18 more
wiley   +1 more source

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