Results 91 to 100 of about 131,732 (302)
Antiretoviral therapy and the lipodystrophy syndrome, part 2: Concepts in aetiopathogenesis [PDF]
, 2001 Clinical research has indicated that the use of nucleoside reverse transcriptase inhibitor (NRTI) and HIV protease inhibitor (PI) therapy is associated with a risk of long-term toxicity syndromes, and that the aetiopathogenesis of these adverse effects ...
Nolan, D., John, M., Mallal, S.
core +1 more source
Fold increase of IC50 of Taiwanese CRF07_BC for various reverse transcriptase inhibitors. [PDF]
, 2017 Fold increase of IC50 of Taiwanese CRF07_BC for various reverse transcriptase inhibitors.
Po-Liang Lu (5309) +11 more
core +1 more source
Brazilian Journal of Infectious DiseasesHuman immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) are the causative agents of AIDS. HIV-2 is prevalent at moderate to high rates in West African countries, such as Senegal, Guinea, Gambia, and Cape Verde.
Maia Hightower, Esper Georges Kallas
doaj +1 more source
Focus on Chirality of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors
Molecules, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Valeria Famiglini, Romano Silvestri
doaj +1 more source
Advanced Science, EarlyView.ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan +5 more
wiley +1 more source
Kaplan-Meier estimates of risk of selective tenofovir discontinuation in boosted protease inhibitors versus non-nucleoside reverse transcriptase inhibitors groups. [PDF]
, 2016 Kaplan-Meier estimates of risk of selective tenofovir discontinuation in boosted protease inhibitors versus non-nucleoside reverse transcriptase inhibitors groups.
Alessandro Cozzi-Lepri (195759) +11 more
core +1 more source
Advanced Science, EarlyView.We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi +15 more
wiley +1 more source
Journal of Global Antimicrobial Resistance: Objective: We evaluated the prevalence of HIV-1 drug resistance in newly diagnosed individuals from 2017 to 2023, in Italy. Methods: Transmitted drug resistance (TDR) was evaluated by using the HIVdb algorithm (https://hivdb.stanford.edu/), through ...
A.C. Ka’e +18 more
doaj +1 more source
BMC Infectious Diseases, 2017 Background The present study aimed to describe the genetic diversity of HIV-1, as well as the resistance profile of the viruses identified in HIV-1 infected pregnant women under antiretroviral therapy in the state of Pará, Northern Brazil.
Luiz Fernando Almeida Machado +6 more
doaj +1 more source
Advanced Science, EarlyView.Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source