Integrated scFv identification and CAR T cell generation for AML targeting in vivo
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu +13 more
wiley +1 more source
Role of Reverse Transcriptase Polymerase Chain Reaction in Cornea Donors During the COVID-19 Pandemic. [PDF]
Arora R +7 more
europepmc +1 more source
Clinical progress note: Rubella
Abstract Rates of rubella infection and congenital rubella syndrome decreased significantly since the introduction of the rubella vaccine in 1969. Endemic rubella was declared eliminated in the United States in 2004, and since 2012, all rubella cases in the United States have been associated with infections acquired abroad.
Adam E. Gailani +2 more
wiley +1 more source
Reverse transcriptase can block polymerase chain reaction
C, Fehlmann, R, Krapf, M, Solioz
openaire +2 more sources
ABSTRACT During the last epidemic in 2015–2016, Zika virus (ZIKV) gaining worldwide attention due to its association with neurological complications such as microcephaly and Guillain‐Barré syndrome. ZIKV can be transmitted through vector‐borne, sexual, maternal‐fetal, and blood transfusion transmission.
Thayane da Encarnação Sá‐Guimarães +4 more
wiley +1 more source
Comparison between the accuracy of chest computerized tomography vs. reverse transcriptase polymerase chain reaction in a tertiary care center in Lebanon; along with their correlation to mortality, morbidity and symptoms in COVID-19 patients. [PDF]
Hanania N +8 more
europepmc +1 more source
The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Carrara, P +11 more
core
Development of Quantitative Competitive—Reverse Transcriptase—Polymerase Chain Reaction for Detection and Quantitation of Avian Leukosis Virus Subgroup J [PDF]
Yongbaek Kim, Tom Brown
openalex +1 more source
Duplex nested reverse transcriptase polymerase chain reaction for simultaneous detection of type 2 porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 from tissue samples [PDF]
Hye Kwon Kim +5 more
openalex +1 more source

