Lamarck and immunity: Somatic and germline evolution of antibody genes [PDF]
Current work on the mechanism of hypermutation of somatically rearranged antibody variable (V) genes shows that the most likely mechanism involves both direct DNA modification (deamination of cytosines to uracils by AID deaminase) and strand nicking plus
Steele, E.J.
core +1 more source
The detection of renal carcinoma cells in the peripheral blood with an enhanced reverse transcriptase-polymerase chain reaction assay for MN/CA9 [PDF]
James M. McKiernan+10 more
openalex +1 more source
Laboratory Diagnosis of Mumps in a Partially Immunized Population: The Nova Scotia Experience
BACKGROUND: In 2007, Atlantic Canada experienced a large outbreak of mumps predominately in university students who had received a single dose of measles, mumps and rubella vaccine.
TF Hatchette+7 more
doaj +1 more source
Diagnostic Accuracy of SARS-CoV-2 Nucleocapsid Antigen Self-Test in Comparison to Reverse Transcriptase-Polymerase Chain Reaction. [PDF]
Sukumaran A+9 more
europepmc +1 more source
Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields [PDF]
We discuss the role of water bridging the DNA-enzyme interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase.
arxiv
A dECM‐based cryogel scaffold with sustained VEGF release is developed to promote angiogenesis in ischemic tissues. Fabricated from decellularized porcine urinary bladder matrix and heparin, the scaffold supports VEGF binding and prolonged release. The cryogel demonstrates enhanced angiogenic potential in vitro and in a murine hindlimb ischemia model ...
Dayeon Roo+7 more
wiley +1 more source
The Agreement Between Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) and Rapid Antigen Test (RAT) in Diagnosing COVID-19. [PDF]
Sahu R, Gupta A, Rawat S, Das A.
europepmc +1 more source
A two stage model for quantitative PCR [PDF]
PCR (Polymerase Chain Reaction), a method which replicates a selected sequence of DNA, has revolutionized the study of genomic material, but mathematical study of the process has been limited to simple deterministic models or descriptions relying on stochastic processes.
arxiv
The detection of disseminated tumor cells in bone marrow from colorectal-cancer patients by a cytokeratin-20-specific nested reverse-transcriptase-polymerase-chain reaction is related to the stage of disease [PDF]
Edlyn Soeth+5 more
openalex +1 more source
Control genes in reverse transcriptase-polymerase chain reaction assays [PDF]
V Kidd, T Lion
openaire +3 more sources