Results 191 to 200 of about 172,121 (249)

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis. [PDF]

Sao Paulo Med J, 2020
Duarte ML, Santos LRD, Contenças ACS, Iared W, Peccin MS, Atallah ÁN.   +5 more
europepmc   +1 more source

Enduring autism‐like phenotypes and deregulated hypothalamic prosocial peptides after early‐life exposure to indoor flame retardants in male C57BL/6 mice

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Polybrominated diphenyl ethers (PBDEs) are neuroendocrine‐disrupting chemicals that produce adverse neurodevelopmental effects. PBDEs have been implicated as risk factors for autism spectrum disorder (ASD), which is characterized by abnormal psychosocial functioning and is commonly comorbid with cognitive deficits and sensory abnormalities ...
Elena V. Kozlova, Gwendolyn M. Gonzalez, Maximillian E. Denys, Anthony E. Bishay, Roberto Gutierrez, Jack Reid, Julia M. Krum, Gregory Lampel, Naran Luvsanravdan, Kayhon M. Rabbani, Jordan Tu, Luis Campoy, Laura M. Anchondo, Crystal N. Luna, Duraan S. Olomi, Eduardo Monarrez, Valeria Carrillo, Jasmin D. Tran, Damon Platt, Yash Korde, Bhuvaneswari D. Chinthirla, Maher Blaibel, Simon Kim, Gladys Chompre, Allison L. Phillips, Heather M. Stapleton, Bernhard Henkelmann, Karl‐Werner Schramm, Margarita C. Curras‐Collazo   +28 more
wiley   +1 more source

Underperformance of Reverse-Transcriptase Polymerase Chain Reaction in Japan and Potential Implications From Diamond Princess Cruise Ship and Other Countries During the Ongoing COVID-19 Pandemic. [PDF]

Int J Health Policy Manag, 2020
Yamamoto K, Ozaki A, Senoo Y, Sawano T, Tanimoto T, Sah R, Wang J.   +6 more
europepmc   +1 more source

Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin‐Dependent NAD+ Regeneration

Molecular Microbiology, Volume 126, Issue 2, Page 208-219, August 2026.
The Lyme disease agent Borrelia burgdorferi has limited metabolic capabilities and depends on salvage of riboflavin via the BB0316‐BB0319 transport system for generation of critical flavin cofactors FMN and FAD. Riboflavin is important for NAD+ regeneration to fuel glycolysis.
Anna M. Schulz, Grace E. Easterling, Aaditya Balasubramaniyan, Mollie W. Jewett   +3 more
wiley   +1 more source

Endogenous RALF peptide function is required for powdery mildew host colonization

New Phytologist, Volume 251, Issue 4, Page 2073-2090, August 2026.
Model of RALF‐FER‐dependent effects on powdery mildew sporulation. Summary The receptor kinase FERONIA (FER) is a susceptibility factor for biotrophic powdery mildew fungal pathogens in Arabidopsis thaliana, but the underlying molecular mechanisms remain largely unknown. FER is required for the perception of endogenous RAPID ALKALINIZATION FACTOR (RALF)
Henriette Leicher, Sebastian D. Schade, Jan W. Huebbers, Kristina S. Munzert‐Eberlein, Genc Haljiti, David Biermann, Athanasios Makris, Xiaoxuan Zhu, Yashank Chauhan, Christina Ludwig, Marion C. Müller, Toshinori Kinoshita, Timo Engelsdorf, Julien Gronnier, Martina K. Ried‐Lasi, Aurélien Boisson‐Dernier, Ralph Hückelhoven, Martin Stegmann   +17 more
wiley   +1 more source

CNGCs in Marchantia paleacea uncouple arbuscular mycorrhizal symbiosis and rhizoid development

New Phytologist, Volume 251, Issue 4, Page 2027-2040, August 2026.
Rhizoid growth and AM fungal infection are uncoupled. Summary In Marchantia paleacea, MpaDMI1‐dependent nuclear Ca2+ oscillations are essential for arbuscular mycorrhizal (AM) fungal colonisation, indicating that endosymbiosis‐mediated nuclear Ca2+ signalling is a conserved feature of land plant–AM symbiosis.
Anson Ho Ching Lam, Aisling Cooke, Jake Richardson, Myriam Charpentier   +3 more
wiley   +1 more source

Recurrent Positive Reverse Transcriptase-Polymerase Chain Reaction Results for Coronavirus Disease 2019 in Patients Discharged From a Hospital in China.

JAMA Netw Open, 2020
Hu R, Jiang Z, Gao H, Huang D, Jiang D, Chen F, Li J.   +6 more
europepmc   +1 more source

Dendritic cell‐specific hypoxia‐inducible factor‐1α deficiency protects mice from recurrent retroviral infection

Experimental Physiology, Volume 111, Issue 8, Page 3843-3856, 1 August 2026.
Abstract Antigen‐processing and ‐presenting cells play a pivotal role in initiation of the antiviral immune response. The cellular adaption of dendritic cells to reduced oxygen and nutrition levels at the site of infection is regulated predominantly by the transcription factor complex hypoxia‐inducible factor‐1 (HIF‐1).
Timm Schreiber, Yvonne Hüsecken, Claudia Lodewick, Simone Schimmer, Gennadiy Zelinskyy, Ulf Dittmer, Kathrin Sutter, Joachim Fandrey, Sandra Winning   +8 more
wiley   +1 more source

The Cavβ4 subunit of Cav1.2 channels antagonizes isoproterenol‐induced hypertrophy in rat cardiac muscle cells by down‐regulating miR‐183‐5p

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract The Cavβ4 subunit of voltage‐gated Cav1.2 channels regulates gene expression in neurons and cardiac cells. It increases the expression of interferon‐β–related genes in H9c2 cardiomyocytes derived from rat ventricular tissue, but the possibility that it also regulates the expression of microRNAs (miRs) remains unexplored.
Elba D. Carrillo, Erick Galicia, María C. García, Jorge A. Sánchez   +3 more
wiley   +1 more source