Results 231 to 240 of about 171,614 (301)
Effects of Cannabidiol on TAFAZZIN‐Deficient B‐Lymphoblastoid Cells
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Deficiency of the cardiolipin remodeling enzyme TAFAZZIN causes Barth syndrome (BTHS), resulting in cardiolipin loss, monolysocardiolipin (MLCL) accumulation, and electron transport chain (ETC) abnormalities in B‐lymphoblastoid cells. Effects of the non‐psychotropic phytocannabinoid cannabidiol (CBD) were examined on B‐lymphoblastoid cells from ...
John Z. Chan +10 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 3, Page 779-803, March 2026.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.Abstract This prospective single‐center study aimed to investigate whether preserving cell‐free ribonucleic acid (cfRNA) in specimens' supernatants (SS) obtained from percutaneous core‐needle biopsy (CNB) of non‐small cell lung cancer (NSCLC) can improve the performance of genomic testing.
Sheng Xu +6 more
wiley +1 more source
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
Advanced Science, Volume 13, Issue 14, 9 March 2026.NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Advanced Science, Volume 13, Issue 14, 9 March 2026.Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication
Advanced Science, Volume 13, Issue 16, 18 March 2026.Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song +11 more
wiley +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu +13 more
wiley +1 more source
Increased incidence of mild cognitive impairment in long COVID patients
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Though brain fog is common in Long‐coronavirus disease 2019 (Long‐COVID), the incidence of mild cognitive impairment (MCI) is unknown. METHODS In an observational cohort study, recovered COVID‐positive, Long‐COVID, and COVID‐negative subjects underwent blinded evaluation using National Alzheimer's Coordinating Center (NACC) and ...
Jennifer A. Frontera +19 more
wiley +1 more source