Results 241 to 250 of about 266,159 (347)

Telomere Length, Epigenetic Age Acceleration, and Mortality Risk in US Adult Populations: An Additive Bayesian Network Analysis

Aging Cell, EarlyView.
Epigenetic DNA methylation‐based (DNAm) clocks, particularly GrimAge epigenetic age acceleration, outperform telomere length in predicting mortality across three US cohorts. Using Additive Bayesian Networks, we uncovered complex links among biological aging markers, sex, race, and mortality risk, highlighting the utility of DNAm‐based biomarkers in ...
May A. Beydoun, Nicole Noren Hooten, Nigus G. Asefa, Michael F. Georgescu, Minkyo Song, Hind A. Beydoun, Sri Banerjee, Jagdish Khubchandani, Osorio Meirelles, Lenore J. Launer, Michele K. Evans, Alan B. Zonderman   +11 more
wiley   +1 more source

Early Detection of Reverse Transcriptase Activity in Plasma of Neonates Infected With HIV-1: A Comparative Analysis With RNA-Based and DNA-Based Testing Using Polymerase Chain Reaction

, 2001
Ronald B. Reisler, Donald M. Thea, Vadim Pliner, Timothy J. Green, Francis Lee, Stephen Nesheim, Teresa Brown, Marcia L. Kalish, Thomas M. Folks, Walid Heneine   +9 more
openalex   +2 more sources

Viral Detection by Reverse Transcriptase Polymerase Chain Reaction in Upper Respiratory Tract and Metagenomic RNA Sequencing in Lower Respiratory Tract in Critically Ill Children With Suspected Lower Respiratory Tract Infection. [PDF]

Pediatr Crit Care Med
Osborne CM, Langelier C, Kamm J, Williamson K, Ambroggio L, Reeder RW, Locandro C, Kirk Harris J, Wagner BD, Maddux AB, Caldera S, Lyden A, Soesanto V, Simões EAF, Leroue MK, Carpenter TC, Hall MW, Zuppa AF, Carcillo JA, Meert KL, Pollack MM, McQuillen PS, Notterman DA, DeRisi J, Mourani PM, National Institute for Child Health and Human Development Collaborative Pediatric Critical Care Research Network.   +25 more
europepmc   +1 more source

Navigating Kidney Transplantation in the Early Phase of Coronavirus Disease 2019: Screening Patients With Reverse Transcriptase Polymerase Chain Reaction and Low-Radiation-Dose Chest Computed Tomography. [PDF]

Transplant Proc, 2021
Butt FK, Julian K, Kadry Z, Jain A.
europepmc   +1 more source

L‐Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU‐08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway

Aging Cell, EarlyView.
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu, Xiaoyun Wu, Yifei Zhang, Yujie Cai, Xinfeng Zhang, Qingwei Zeng, Jie Luo, Jing Wei, Tingtao Chen   +8 more
wiley   +1 more source

Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management

Australian Veterinary Journal, EarlyView.
Progressive feline leukaemia virus (FeLV) infection dramatically shortens the lives of infected cats, causing acquired immunodeficiency, aplastic anaemia, lymphoma, leukaemia and other myeloproliferative diseases. The potential impact of regressive FeLV infection on the development of disease remains largely unknown, although there is evidence it ...
ME Westman, SJ Coggins, M van Dorsselaer, JM Norris, RA Squires, M Thompson, R Malik   +6 more
wiley   +1 more source

Anaplastic large cell lymphoma in children and adolescents

British Journal of Haematology, EarlyView.
Summary Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of chromosomal translocations involving the ALK gene at chromosome 2p23.
Eric J. Lowe, Wilhelm Woessmann
wiley   +1 more source

First Detection of SARS-CoV-2 by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Assay in Pleural Fluid. [PDF]

Chest, 2020
Mei F, Bonifazi M, Menzo S, Di Marco Berardino A, Sediari M, Paolini L, Re A, Gonnelli F, Duranti C, Grilli M, Vennarucci GS, Latini MA, Zuccatosta L, Gasparini S.   +13 more
europepmc   +1 more source

Quantification of mRNA for the vitamin D metabolizing enzymes CYP27B1 and CYP24 and vitamin D receptor in kidney using real-time reverse transcriptase- polymerase chain reaction [PDF]

, 2003
Paul Anderson, Peter D. O’Loughlin, BK May, HA Morris   +3 more
openalex   +1 more source

Tumor‐Associated Neutrophils Regulate Breast Cancer Progression Through the AQP9/STAT3 Signaling Pathway

Cancer Science, EarlyView.
Tumor‐associated neutrophils (TANs) enhance STAT3 phosphorylation by upregulating aquaporin 9 (AQP9) to promote breast cancer (BC) progression. AQP9 may be crucial for TAN‐mediated BC progression and is a novel target for immunotherapy in patients with BC.
Wuqin Xu, Guilu Zhu, Youjing Sheng, Wenjun Zhang, Shujing Wang, Qiang Wu   +5 more
wiley   +1 more source