Results 241 to 250 of about 171,614 (301)
Brain and Behavior, Volume 16, Issue 3, March 2026.Assessment of pTERT subtypes of glioblastoma by quantitative FLAIR analysis based on fusing MRI images, Participants, Methods, Results, Glioblastoma patients, Segmented to 3 subregions Investigated the significant metrics of subregions and other clinical‐imaging factors Prediction models of pTERT Tested in validation cohorts pTERTm, pTERTw, Conclusion:
Bocong Gao +3 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.We identified a SNP (rs373245753, T>G) in the 3′UTR of the CAPZA1 gene from the dbSNP, this study uncovers a novel molecular mechanism which CAPZA1[T] acts as a tumor suppressor by binding to hnRNP K and PTPB1 to influence its mRNA stability, offering potential implications for therapeutic targeting. These results provide insights into the central role
Nan Kang +5 more
wiley +1 more source
Consensus recommendations in the management of jaw (gnathic) osteosarcoma
Cancer, Volume 132, Issue 5, 1 March 2026.Abstract Gnathic osteosarcoma (OS), which includes mandibular and maxillary jaw OSs, account for 6%–9% of OS. Single‐institutional and multi‐institutional retrospective studies, as well as population‐level databases, suggest that clinical differences exist among gnathic OS and OS of other sides, including other craniofacial OS.
Matthew S. Dietz +22 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.NME3 deficiency disrupts mitochondrial fission‐fusion balance, causing neuronal damage via ROS. Pharmacological Drp1 inhibition (Mdivi‐1) or substantia nigra‐specific NME3 overexpression restores mitochondrial equilibrium, prevents dopaminergic neuron loss, and alleviates motor deficits in PD models.
Chen Qiao +5 more
wiley +1 more source
Current Protocols, Volume 6, Issue 3, March 2026.Abstract RNA‐based therapeutics are emerging as a powerful platform for disease treatment, and one of the novel RNA molecules with therapeutic potential is circular RNA (circRNA). The ubiquitously expressed circRNAs are covalently closed, single‐stranded RNA molecules formed by backsplicing and are known to regulate gene expression by either sponging ...
Pragnya Das +3 more
wiley +1 more source
Transposable elements: Functional aspects and applications as drivers of crop innovation
Crop Science, Volume 66, Issue 2, March/April 2026.Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.A depiction of reconstituted red sorghum and black sorghum extract effects on HT‐29 and CCD 841 CoN cell cells at 500 and 2000 μg/mL for 12 and 24 h resulting in the decrease of cancer cell viability, modulation of mutation‐associated genes, and suppression of hypoxia and metabolic signaling.
Aduba Collins +4 more
wiley +1 more source
Protective Effect of Protaetia brevitarsis Larvae Extract on Alcoholic Liver Disease in Mice
Food Science &Nutrition, Volume 14, Issue 3, March 2026.This study evaluated the hepatoprotective effects of Protaetia brevitarsis larvae water extract (PBLE) in a chronic‐plus‐binge ethanol mouse model. PBLE attenuated hepatic lipid accumulation and liver injury by modulating alcohol metabolism‐related enzymes and reducing oxidative stress and inflammation.
Sueun Lee +6 more
wiley +1 more source
ALKBH5‐Driven m6A Demethylation Boosts Inflammation and Autophagy in LPS‐Stimulated Macrophages
Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.ABSTRACT Purpose Acute Respiratory Distress Syndrome (ARDS) remains a critical health threat with limited pharmacological treatments. This study investigates the role of the N6‐methyladenosine (m6A) demethylase AlkB homolog 5 (ALKBH5) in alveolar macrophages and its subsequent impact on inflammation and autophagy during ARDS pathogenesis.
Gui Wang, Ting Zhou, Shujun Zhou
wiley +1 more source