Results 121 to 130 of about 329,236 (311)

3D Bioprinting‐Assisted Engineering of Stem Cell‐Laden Hybrid Biopatches With Distinct Geometric Patterns Considering the Mechanical Characteristics of Regular and Irregular Connective Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid biopatch platform integrating 3D printed polymeric patterns with stem cell‐laden collagen bioinks is developed to mimic the mechanical properties of connective tissues. By tailoring geometric architectures, the constructs replicate anisotropic or isotropic mechanics, enhancing tissue‐specific regeneration.
Minjun Ahn   +6 more
wiley   +1 more source

Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon‐to‐Bone Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
The authors have developed a biomimetic scaffold with dual gradients through a diffusion‐driven method. The scaffold features funnel‐shaped microchannels for cell infiltration, while the dual gradients synergetically induce the graded differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, and tenocytes, allowing for a seamless ...
Min Hao   +3 more
wiley   +1 more source

Multiplex Reverse Transcription Polymerase Chain Reaction Combined with a Microwell Hybridization Assay Screening for Arbovirus and Parasitic Infections in Febrile Patients Living in Endemic Regions of Colombia. [PDF]

open access: yesTrop Med Infect Dis, 2023
Calderon-Ruiz P   +10 more
europepmc   +1 more source

Quantitative mRNA Expression Analysis from Formalin-Fixed, Paraffin-Embedded Tissues Using 5′ Nuclease Quantitative Reverse Transcription-Polymerase Chain Reaction [PDF]

open access: bronze, 2000
Tony E. Godfrey   +6 more
openalex   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam   +9 more
wiley   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

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