Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen+12 more
wiley +1 more source
Single-step multiplex reverse transcription-polymerase chain reaction for the detection and differentiation of QX-like infectious bronchitis virus from the Thai variant and vaccine strains H120, Ma5, and 4/91. [PDF]
Junnu S, Pohuang T.
europepmc +1 more source
Detection of Recurrent Thyroid Cancer by Sensitive Nested Reverse Transcription-Polymerase Chain Reaction of Thyroglobulin and Sodium/Iodide Symporter Messenger Ribonucleic Acid Transcripts in Peripheral Blood1 [PDF]
Rosa Paula M. Biscolla+2 more
openalex +1 more source
Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu+9 more
wiley +1 more source
Comparison of Commercially Available Thermostable DNA Polymerases with Reverse Transcriptase Activity in Coupled Reverse Transcription Polymerase Chain Reaction Assays. [PDF]
Smirnova EV+5 more
europepmc +1 more source
Development of a One-Step Real-Time TaqMan Reverse Transcription Polymerase Chain Reaction (RT-PCR) Assay for the Detection of the Novel Variant Infectious Bursal Disease Virus (nVarIBDV) Circulating in China. [PDF]
Wang C, Hou B, Shao G, Wan C.
europepmc +1 more source
Comparison of Virus Isolation, Reverse Transcription-Polymerase Chain Reaction, Immunohistochemistry, and in Situ Hybridization for the Detection of Porcine Reproductive and Respiratory Syndrome Virus from Naturally Aborted Fetuses and Stillborn Piglets [PDF]
Doo‐Sung Cheon, Chanhee Chae
openalex +1 more source
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi+8 more
wiley +1 more source
Comparative Analysis of Viral Load Quantification Using Reverse Transcription Polymerase Chain Reaction and Digital Droplet Polymerase Chain Reaction. [PDF]
Gebe Abreu Cabral P+9 more
europepmc +1 more source