Results 41 to 50 of about 22,637 (304)

Fidelity and Reversibility in the Three Body Problem

open access: yes, 2016
We use the Reversibility Error Method and the Fidelity to analyze the global effects of a small perturbation in a non-integrable system. Both methods have already been proposed and used in the literature but the aim of this paper is to compare them in ...
CIOTTI, LUCA, Turchetti, G., Panichi, F.
core   +1 more source

Rapidly converging chaos indicator for studying dynamic aperture in a storage ring with space charge

open access: yesPhysical Review Accelerators and Beams, 2020
The determination of dynamic aperture in storage rings and colliders is a numerically intensive procedure. When realistic space-charge forces come into consideration, the numerical load becomes even heavier. Furthermore, dynamic aperture estimation using
Kilean Hwang, Chad Mitchell, Robert Ryne
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A novel two-dimensional reversible data hiding method with high embedding capacity in H.264/advanced video coding

open access: yesInternational Journal of Distributed Sensor Networks, 2020
Developing the technology of reversible data hiding based on video compression standard, such as H.264/advanced video coding, has attracted increasing attention from researchers.
Yi Chen   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Morning Glory Disc Anomaly, A Report of a Successfully Treated Case of Functional Amblyopia [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Morning Glory Disc Anomaly (MGDA) is a congenital malformation of the optic nerve characterized by the presence of a funnel-shaped macropapilla with neuroglial remnants in its center surrounded by an elevated and pigmented chorioretinal ring.
Humberto Cavazos-Adame   +3 more
doaj   +1 more source

Pipelined information flow in molecular mechanical circuits leads to increased error and irreversibility

open access: yes, 2023
Pipelining is a design technique for logical circuits that allows for higher throughput than circuits in which multiple computations are fed through the system one after the other.
Seet, Ian   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Cylindrical vector beam multiplexer/demultiplexer using off-axis polarization control

open access: yesLight: Science & Applications, 2021
The emergence of cylindrical vector beam (CVB) multiplexing has opened new avenues for high-capacity optical communication. Although several configurations have been developed to couple/separate CVBs, the CVB multiplexer/demultiplexer remains elusive due
Shuqing Chen   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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