Results 71 to 80 of about 86,016 (287)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Toward a storage ring coherent light source based on an angular dispersion-induced microbunching scheme

Journal of Synchrotron Radiation
The combination of reversible angular dispersion-induced microbunching (ADM) and the rapid damping storage ring provides a storage-ring-based light source with the capability to produce longitudinal coherent radiation with a high repetition rate.
Changliang Li, Bocheng Jiang, Chao Feng, Qiang Gu, Zhenghe Bai, Weishi Wan, Qinglei Zhang, Kun Wang   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Reversible Cyclic Codes over F2+uF2+u2F2

, 2022
In this article, we investigate the formation of reversible cyclic codes (i.e., its codewords forms a symmetry) over the ring S=F2+uF2+u2F2, where u3=0.
Mohd Azmi, Nadeem ur Rehman, Amal S. Alali   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Rings over which skew hurwitz polynomial rings are reversible and their extensions [PDF]

, 2020
Bu çalışmada; bir halkanın terslenebilir olması kavramı, o halka üzerine kurulan skew Hurwitz polinomlar halkasına genişletilerek, zayıf skew Hurwitz terslenebilir (kısaca zayıf ...-terslenebilir) halka kavramı tanıtılmıştır.
Kaynarca, Fatma
core   +1 more source

Non‐daily contraception: Reinforcing the choice of users and addressing unmet needs of reproductive health

Acta Obstetricia et Gynecologica Scandinavica
Despite great societal efforts promoting female autonomy, Sweden still faces unmet contraceptive needs, with abortion rates being the highest in the Nordic countries.
Helena Kopp Kallner, Ingela Lindh, Kristina Gemzell‐Danielsson   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Unexpected Entropy-Driven Ring-Opening Polymerization in a Reversible Supramolecular System

, 2016
Unexpected Entropy-Driven Ring-Opening Polymerization in a Reversible Supramolecular ...
E. W. Meijer (1454104), Rint P. Sijbesma (1788136), Brigitte J. B. Folmer (2984208)   +2 more
core   +1 more source