Results 181 to 190 of about 177,535 (259)

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

High‐throughput, high‐fidelity reconstruction of whole mouse‐heart cytoarchitecture at cellular scale

The Journal of Physiology, EarlyView.
Abstract figure legend Experimental workflow of the dual‐camera light‐sheet microscope (dual‐mesoSPIM) pipeline. Intact adult mouse hearts undergo CUBIC‐based delipidation and refractive‐index matching, rendering the whole organ optically transparent (left).
Francesco Giardini, Chiara Palandri, Sofia Botti, Camilla Olianti, Paolo Mele, Niccolò Ballerini, Roberto Piersanti, Mauro Giacca, Peter Kohl, Callum M. Zgierski‐Johnston, Elisabetta Cerbai, Francesco Regazzoni, Leonardo Sacconi   +12 more
wiley   +1 more source

Epochenmachende Neuheit Rex, Dreyer s Fruchtsaft-Apparat

EPOCHENMACHENDE NEUHEIT REX, DREYER S FRUCHTSAFT-APPARAT Epochenmachende Neuheit Rex, Dreyer s Fruchtsaft-Apparat ( -
Rex- Werke
core  

Restoration of neuromuscular function by mitochondrial transplantation in injured mouse skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Mice received chemical injury (cardiotoxin) in the tibialis anterior muscle of one limb, and the contralateral muscle was injected with phosphate‐buffered saline (PBS) as a sham control. Mice then received PBS or mitochondria suspended in PBS into the tail vein.
Stephen E. Alway, Peter J. Ferrandi, Hector G. Paez, Christopher R. Pitzer, Junaith S. Mohamed, Michael R. Deschenes, James A. Carson   +6 more
wiley   +1 more source

Channelrhodopsin ion selectivity determines mechanisms and efficacy of optogenetic defibrillation in human atria and ventricles

The Journal of Physiology, EarlyView.
Abstract figure legend A, we used in silico models of human cardiomyocytes and microelectrode recordings on transgenic zebrafish hearts to study electrophysiology during optogenetic perturbations. Specifically, we compared effects of three distinct classes of channelrhodopsins: the cation non‐selective Chlamydomonas reinhardtii channelrhodopsin‐2 (ChR2)
Sophia Ohnemus, Albert Dasí, Ahmed F. Ramadan, Joachim Greiner, Eike M. Wülfers, Matthew R. Stoyek, Linda Tillert, Johannes Vierock, T. Alexander Quinn, Peter Kohl, Patrick M. Boyle, Viviane Timmermann, Franziska Schneider‐Warme   +12 more
wiley   +1 more source

Biological Flora of New Zealand 17: Kunzea ericoides (Myrtaceae), Kānuka

New Zealand Journal of Botany, Volume 64, Issue 4, December 2026.
This review summarises the taxonomic status, morphology, physiology, ecology, plant communities, mycological, invertebrate and vertebrate interactions and human use of the New Zealand endemic tree Kunzea ericoides (A. Rich.) Joy Thomps. (kānuka) (Myrtaceae).
P. J. Bellingham, M. S. McGlone, I. A. Dickie, N. Harcourt, P. B. Heenan, J. K. McCarthy, C. H. Watts, M. C. Smale, S. J. Richardson   +8 more
wiley   +1 more source

The novel regulatory influence of Argonaute 1 on messenger RNA 5‐methylcytosine modification in Arabidopsis thaliana

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract 5‐Methylcytidine (m5C) modifications play a critical role in RNA metabolism. TRM4B (tRNA‐specific methytransferase 4B) is the only known component of the plant m5C machinery that mediates mRNA (messenger RNA) methylation. To date, no regulators governing site‐specific m5C modifications have been identified, apart from several degenerated ...
Zedi Feng, Xiu Yin, Zhifang Jiang, Jia Yao, Yiling Dong, Xiaoxia Ma, Yijun Meng   +6 more
wiley   +1 more source

Transcriptome analysis identifies key miRNAs involved in the regulation of rabbit intramuscular fat deposition. [PDF]

BMC Genomics
Song G, Wang H, Jin Z, Duan Q, Ahamba IS, Wang S, Ren Z, Dong X.   +7 more
europepmc   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

Journal of Cutaneous Pathology, Volume 53, Issue 12, Page 1165-1171, December 2026.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond, Victoria Soto, Beatriz Abdo Abujamra, Franco Rongioletti, John A. McGrath, Ivan Jozic, Paolo Romanelli   +6 more
wiley   +1 more source

M⁶A Regulates Intramuscular Fat Deposition in Rabbits Through <i>LPL</i>/3-Methyl-L-Histidine/Pathways. [PDF]

Animals (Basel)
Luo G, Le J, Mao X, Xue T, Ren Z.
europepmc   +1 more source