Results 111 to 120 of about 1,141 (182)

Antifungal Agents in the 21st Century: Advances, Challenges, and Future Perspectives

Infectious Disease Reports
Invasive fungal infections (IFIs) represent a growing global health threat, particularly for immunocompromised populations, with mortality exceeding 1.5 million deaths annually.
Francesco Branda, Nicola Petrosillo, Giancarlo Ceccarelli, Marta Giovanetti, Andrea De Vito, Giordano Madeddu, Fabio Scarpa, Massimo Ciccozzi   +7 more
doaj   +1 more source

Candidemia: Evolution of Drug Resistance and Novel Therapeutic Approaches

Infection and Drug Resistance, 2021
Anna Maria Tortorano,1 Anna Prigitano,1 Gianluca Morroni,2 Lucia Brescini,2,3 Francesco Barchiesi2,4 1Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milano, Italy; 2Department of Biomedical Sciences and Public Health ...
Tortorano AM, Prigitano A, Morroni G, Brescini L, Barchiesi F   +4 more
doaj  

Primary antifungal prophylaxis in hematological malignancies. Updated clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL). [PDF]

At the 10th European Conference on Infections in Leukaemia (ECIL), the guidelines for antifungal prophylaxis in pediatric and adult patients with hematological malignancies (HM) were updated and some changes introduced.
Blennow, O., Blijlevens, N.M.A., Busca, A., Cordonnier, C., Lamoth, F., Maertens, J., Maschmeyer, G., Pagano, L., Spadea, M., Xhaard, A.   +9 more
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FDA-Approved Antibacterials and Echinocandins [PDF]

Since 1955, a total of 12 peptide-based drugs with antimicrobial or antifungal properties have received approval from the Food and Drug Administration (FDA).
Al Musaimi O
core  

Candida Auris Features and its Treatment: Global Emergency [PDF]

Fungal pathogen Candida auris was identified in 2009, in Japan. Currently, it is identified in 5 continents, in more than 40 countries. Therefore, it is nowadays defined as critical priority pathogen.
Durán, Nelson, Fávaro, Wagner J, Nakazato, Gerson   +2 more
core   +2 more sources

Innovative antifungal strategies to combat drug-resistant Candida auris: recent advances and clinical implications

Frontiers in Cellular and Infection Microbiology
Candida auris is an invasive fungal pathogen recognized globally as a significant health threat due to its marked resistance to multiple classes of antifungal agents, including azoles, echinocandins, and polyenes.
Wei Du, Qihui Wang, Min Zhao
doaj   +1 more source

Candidemia: An Update on Epidemiology, Risk Factors, Diagnosis, Susceptibility, and Treatment

Pathogens
Candidemia is a highly prevalent invasive fungal infection caused primarily by C. albicans, C. parapsilosis, C. glabrata (currently Nakaseomyces glabratus), C. tropicalis, and C. krusei (currently Pichia kudriavzevii). Risk factors for the development of
Juan Pablo Cabrera-Guerrero, Eduardo García-Salazar, Graciela Hernandez Silva, Alberto Chinney Herrera, Erick Martínez-Herrera, Rodolfo Pinto-Almazán, María Guadalupe Frías-De-León, Carlos Alberto Castro-Fuentes   +7 more
doaj   +1 more source

Exploring a Therapeutic Gold Mine:The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin [PDF]

Human fungal infections comprise systemic mycoses as well as various skin diseases. Rising case numbers along with inefficient therapies and the appearance of drug-resistant strains unleashed a considerable health problem over the last years.
Biersack, Bernhard, Ma, Jingyi, van de Sande, Wendy   +2 more
core   +1 more source

Epidemiology of Invasive Candidiasis. [PDF]

Invasive candidiasis (IC) is an increasingly prevalent, costly, and potentially fatal infection brought on by the opportunistic yeast, Candida. Previously, IC has predominantly been caused by C. albicans which is often drug susceptible.
Bays, Derek, Chiller, Tom, Hoenigl, Martin, Jenkins, Emily, Lyman, Meghan, Ostrosky-Zeichner, Luis, Pappas, Peter, Strong, Nora, Thompson Iii, George   +8 more
core   +1 more source

Title: Synergism between Fluconazole and Terminalia catappa Extract and its Use in the Treatment of Candida-infected Tenebrio molitor Larvae / Título: Sinergismo entre Fluconazol e o Extrato de Terminalia catappa e seu uso no tratamento de larvas de Tenebrio molitor infectadas com Candida [PDF]

, 2020
The increase of Candida infections in the last few decades is alarming and the resistance development to antifungals, especially fluconazole, the most widely used drug for treatment, enhances the importance of these infections.
Andrade Monteiro, Cristina de, Barros Filho, Alan Kardec Duailibe, dos Santos, Julianna Ribeiro Alves, Galvão Rocha, Flaviane Maria, Lima Campos, Carmem Duarte, Lopes Rocha, Carlos Henrique, Nascimento da Silva, Luis Claúdio, Silva Mendonça, Aline Michelle   +7 more
core   +1 more source