Results 151 to 160 of about 798,356 (283)

A multifactorial intervention to improve cardiovascular outcomes in adults with type 2 diabetes and current or previous diabetic foot ulcer disease: Protocol for a multi‐centre randomised control trial (MiFoot study)

Diabetic Medicine, EarlyView.
Abstract Background In the United Kingdom, the prevalence of diabetes‐related foot ulcer disease (DFUD) is 6.3%, and cardiovascular disease (CVD) is the leading cause of mortality in people with DFUD. This study aims to evaluate the effectiveness of a multifactorial intervention to reduce CVD events and mortality in adults with type 2 diabetes (T2D ...
Tolu Onuwe, Patrick J. Highton, David Batchelor, Alan Brennan, Molly Caba, Melanie J. Davies, Mark P. Funnell, Frances Game, Clare L. Gillies, Agnieszka Glab, Laura J. Gray, Edward Gregg, Michelle Hadjiconstantinou, Vicky Hall, Vicki Johnson, John R. Petrie, Dan Pollard, Hannah Rowntree, Solomon Tesfaye, Jonathan Valabhji, David Webb, Francesco Zaccardi, Kamlesh Khunti   +22 more
wiley   +1 more source

Genetic evidence for the effects of glucokinase activation on frailty‐related outcomes: A Mendelian randomisation study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims We aimed to use the Mendelian randomisation (MR) design to investigate the potential causal effects of glucokinase (GK) activation on frailty‐related outcomes and to explore the potential mediating effects of metabolic and inflammatory biomarkers.
Rong Hua, Mai Shi, Elaine Chow, Aimin Yang, Yin Ting Cheung   +4 more
wiley   +1 more source

Assessment of Unexpected (Non-ABO) Red Blood Cell Antibodies and Their Associated Clinical Conditions Among Patients and Blood Donors Attending University Teaching Hospital of Kigali (CHUK) and Rwanda Blood Transfusion Division. [PDF]

Adv Hematol
Niyibizi JB, Seifu D, Geurkink C, Formiller E, Muyombo T, Gashaija C, Uwayo HD, Uwizeyimana G, Gillard L.   +8 more
europepmc   +1 more source

The Allelic and Phenotypic Frequencies of the ABO and Rh Blood Types in Pregnant Women in Addis Ababa, Ethiopia. [PDF]

Biomed Res Int
Tedbabe MW, Birri DJ, Desta TT.
europepmc   +1 more source

Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism

The FEBS Journal, EarlyView.
SUCNR1, activated by succinate, is a Gi‐ and Gq‐coupled receptor present at the plasma membrane and in endosomes. There are conflicting reports about the pro‐/anti‐inflammatory effects of the succinate‐SUCNR1 signaling axis, and these are likely due to localization‐dependent signaling.
Aenne‐Dorothea Liebing, Philipp Rabe, Petra Krumbholz, Christian Zieschang, Franziska Bischof, Angela Schulz, Susan Billig, Claudia Birkemeyer, Thanigaimalai Pillaiyar, Mikel Garcia‐Marcos, Robert Kraft, Claudia Stäubert   +11 more
wiley   +1 more source

Impact of perioperative dexmedetomidine treatment on 1-year mortality in patients undergoing orthotopic heart transplantation. [PDF]

BJA Open
Torregroza C, Endreß CL, M'Pembele R, Roth S, Stroda A, Aubin H, Lichtenberg A, Buse GL, Huhn R, Boeken U.   +9 more
europepmc   +1 more source

Blood Purity and Scientific Independence : Blood Science and Postcolonial Struggles in Korea, 1926–1975

, 2019
Hyun, J.
core   +1 more source

Subjective Physical Performance and Its Determinants in Patients With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Physical functioning is compromised in patients with haemophilia (PwH). However, factors negatively influencing subjective physical performance (SPP) remain underexplored. Hence, this study aimed to compare the SPP of PwH with healthy controls (CON), to differentiate them based on disease‐specific, person‐related, and arthropathy ...
Alexander Schmidt, Fabian Tomschi, Pia Möllers, Marius Brühl, Sylvia von Mackensen, Andreas C. Strauss, Heinrich Richter, Johannes Oldenburg, Thomas Hilberg   +8 more
wiley   +1 more source

Efficacy and prognostic impact of preoperative risk factors for salvage liver transplantation and repeat hepatectomy in patients with early-stage recurrent hepatocellular carcinoma: a propensity score-matched analysis. [PDF]

Front Oncol
Yang L, Huang Y, Deng D, Liu J, Xu L, Yi P.   +5 more
europepmc   +1 more source

Rethinking HIV treatment: How non‐integrase strand regimens may hold the key to better immune health

HIV Medicine, EarlyView.
Abstract Purpose HIV outcome changed drastically with antiretroviral (ARV) therapy, especially after the introduction of second‐generation integrase strand transfer inhibitors (INSTIs). Despite these advances, however, chronic immune activation and exhaustion, marked by programmed cell death 1 (PD‐1) and programmed death ligand 1 (PD‐L1) upregulation ...
Bogusz Aksak‐Wąs, Karolina Skonieczna‐Żydecka, Miłosz Parczewski, Rafał Hrynkiewicz, Filip Lewandowski, Karol Serwin, Kaja Mielczak, Franciszek Lenkiewicz, Paulina Niedźwiedzka‐Rystwej   +8 more
wiley   +1 more source