Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses
Ecology and Evolution, Volume 14, Issue 6, June 2024.We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Anna R. Sjodin +3 more
wiley +1 more source
Two herpesviral noncoding PAN RNAs are functionally homologous but do not associate with common chromatin loci. [PDF]
PLoS Pathogens, 2018 During lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV), a nuclear viral long noncoding RNA known as PAN RNA becomes the most abundant polyadenylated transcript in the cell. Knockout or knockdown of KSHV PAN RNA results in loss of late
Johanna B Withers +4 more
doaj +1 more source
B-cell-independent lymphoid tissue infection by a B-cell-tropic rhadinovirus
Journal of General Virology, 2015 Lymphocytes provide gammaherpesviruses with a self-renewing substrate for persistent infection and with transport to mucosal sites for host exit. Their role in the initial colonization of new hosts is less clear. Murid herpesvirus 4 (MuHV-4), an experimentally accessible, B-cell-tropic rhadinovirus (gamma-2 herpesvirus), persistently infects both ...
Chao, Brittany +2 more
openaire +3 more sources
The Rhesus Rhadinovirus CD200 Homologue Affects Immune Responses and Viral Loads during In Vivo Infection [PDF]
Journal of Virology, 2014 ABSTRACT Rhesus macaque rhadinovirus (RRV) is a gammaherpesvirus of rhesus macaque (RM) monkeys that is closely related to human herpesvirus 8 (HHV-8)/Kaposi's Sarcoma-associated herpesvirus (KSHV), and it is capable of inducing diseases in simian immunodeficiency virus (SIV)-infected RM that are similar to those seen in humans ...
Ryan D, Estep +8 more
openaire +2 more sources
Interaction of gamma-herpesvirus genome maintenance proteins with cellular chromatin.
PLoS ONE, 2013 The capacity of gamma-herpesviruses to establish lifelong infections is dependent on the expression of genome maintenance proteins (GMPs) that tether the viral episomes to cellular chromatin and allow their persistence in latently infected proliferating ...
Nouman Mughal +4 more
doaj +1 more source
Virology Journal, 2007 Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses.
Nitsche Andreas +4 more
doaj +1 more source
An outbreak of sheep-associated malignant catarrhal fever in sows [PDF]
, 2009 his paper describes a case of malignant catarrhal fever in a sow herd in Belgium caused by infection with ovine herpesvirus-2 (OHV-2). The 11 affected sows had high fever and 10 of them died within 3 days after the onset of clinical disease.
Kerkhofs, P +7 more
core +1 more source
KSHV/HHV-8 and HIV infection in Kaposi's sarcoma development [PDF]
, 2007 Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion affecting the skin, lymphnodes and viscera, which develops from early inflammatory stages of patch/plaque to late, nodular tumors composed predominant of spindle cells (SC ...
Pyakurel, P. +4 more
core +1 more source
Maturation and Vesicle-Mediated Egress of Primate Gammaherpesvirus Rhesus Monkey Rhadinovirus Require Inner Tegument Protein ORF52 [PDF]
Journal of Virology, 2014 ABSTRACT The tegument layer of herpesviruses comprises a collection of proteins that is unique to each viral species. In rhesus monkey rhadinovirus (RRV), a close relative of the human oncogenic pathogen Kaposi's sarcoma-associated herpesvirus, ORF52 is a highly abundant tegument protein tightly associated with the capsid.
Melissa S, Anderson +2 more
openaire +2 more sources
Subcellular fractionation method to study endosomal trafficking of Kaposi’s sarcoma-associated herpesvirus [PDF]
, 2016 Background Virus entry involves multiple steps and is a highly orchestrated process on which successful infection collectively depends. Entry processes are commonly analyzed by monitoring internalized virus particles via Western blotting, polymerase ...
A Greiner +41 more
core +2 more sources